thalidomide-piperazine

Thalidomide-Piperazine 5-fluoride is a compound synthesized as an E3 ligase ligand-linker conjugate, incorporating a cereblon ligand derived from Thalidomide and utilizing a linker commonly employed in PROTAC technology.

Thalidomide-Piperazine-PEG1-NH2 is a synthetic E3 ligase ligand-linker conjugate, featuring a cereblon ligand based on Thalidomide and a single linker.

Thalidomide-piperazine-(S)-CH2-pyrrolidine-C2-O-CH2-COO-C(CH3)3 is a synthetic ligand-linker conjugate for E3 ligase. It features a Thalidomide-based cereblon ligand and a linker. This compound can be utilized in the synthesis of PROTAC BET degraders.

(S)-Thalidomide-piperazine-pyrimidine-piperazine-C2-O-CH2-COO-C(CH3)3 is an E3 ligase ligand-linker conjugate (E3LigaseLigand-Linker Conjugates) composed of thalidomide and its corresponding linker. This compound functions as a Cereblon ligand, facilitating the recruitment of CRBN protein, and serves as a crucial intermediate in the synthesis of complete PROTAC molecules.

(S)-Thalidomide-piperazine-pyrimidine-piperazine-C2-O-C2-OH is a conjugate combining an E3 ligase ligand with a linker (E3LigaseLigand-Linker Conjugates), composed of Thalidomide and the corresponding Linker. This compound functions as a Cereblon ligand, recruiting the CRBN protein and serving as a crucial intermediate in the synthesis of complete PROTAC molecules.

(S)-Thalidomide-piperazine-pyrimidine-piperazine-C2-OH is a conjugate of an E3 ligase ligand and a linker (E3LigaseLigand-Linker Conjugates), consisting of Thalidomide and the corresponding Linker. It functions as a Cereblon ligand to recruit the CRBN protein and serves as a crucial intermediate for synthesizing complete PROTAC molecules.

(S)-Thalidomide-piperazine-(1S,4r)-cyclohexane-NH-Boc is a conjugate of an E3 ligase ligand and a linker (E3LigaseLigand-Linker Conjugates), composed of Thalidomide and the corresponding Linker. It functions as a Cereblon ligand to recruit CRBN protein and serves as a crucial intermediate for synthesizing complete PROTACs molecules.

Thalidomide-piperazine-Boc, an intermediate used in the synthesis of BCL6 PROTAC, targets the B-cell lymphoma 6 protein.

Thalidomide-Piperazine-Piperidine is a compound composed of a synthesized E3 ligase ligand-linker conjugate. It combines a cereblon ligand derived from Thalidomide with a linker commonly used in PROTAC technology.

Thalidomide-Piperazine-PEG2-NH2 is a synthetic E3 ligase ligand-linker conjugate combining the cereblon ligand derived from Thalidomide with a linker commonly used in PROTAC technology.

Thalidomide-Piperazine-PEG3-NH2 is a synthesized E3 ligase ligand-linker conjugate that combines a Thalidomide-based cereblon ligand with a linker commonly used in [PROTAC] technology, functioning as an E3 ligase recruiter.

Thalidomide-Piperazine-Piperidine hydrochloride is a synthesized compound serving as an E3 ligase ligand-linker conjugate, combining the cereblon ligand derived from Thalidomide with a linker commonly used in PROTAC technology.

Thalidomide-Piperazine 5-fluoride hydrochloride, a derivative of the cereblon (CRBN) inhibitor Thalidomide, serves as a ligand for E3 ubiquitin ligase (Ligands for E3 Ligase), facilitating the synthesis of PROTACs [1].

E3ligaseLigand-Linker Conjugate 30 is a compound made by conjugating an E3 ligase ligand, Thalidomide, with a linker. This conjugate functions as a Cereblon ligand to recruit CRBN protein and serves as a crucial intermediate in the synthesis of complete PROTACs molecules.

Thalidomide-piperidine-CO-piperazine-C-3-Br-Ph is a type of E3 ubiquitin ligase ligand-linker conjugate (E3 Ligase Ligand-Linker Conjugates). It is utilized in the synthesis of PROTAC SMARCA2 degrader-28.

Thalidomide-piperidine-C2-piperazine-Boc is an E3 Ligase Ligand-linker conjugate comprising a cereblon ligand based on Thalidomide and a linker. This compound is utilized in the synthesis of PROTAC.

Thalidomide-5-piperazine-C-piperidine-CO-C8-NH2 is a coupled compound acting as an E3 ubiquitin ligase ligand-linker conjugate.

Thalidomide-5-piperazine is a PROTAC target protein ligand.

PROTAC ER Degrader-14 (compound 86) is a PROTAC-type estrogen receptor ERR degrader. It comprises an E3 ubiquitin ligase ligand (blue part) (S)-Deoxy-thalidomide, a PROTAC linker (black part) N-Boc-piperazine, and a target protein ligand (red part) ER ligand-6. The combination of the E3 ligase and linker forms tert-Butyl (S)-4-(2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-5-yl)piperazine-1-carboxylate.