tbz

(+)-Tetrabenazine ((3R,11bR)-Tetrabenazine) is a reversible vesicular monoamine transporter 2 (VMAT-2) inhibitor, inhibits transport by VMAT2 with 10-fold greater potency than transport by VMAT1.

TBZ-1 is a fluorescent probe designed to monitor the activity of the immunoproteasome (iCP) within cells. Upon selective cleavage by β5i, TBZ-1 becomes fluorescently activated, making it suitable for intracellular activity monitoring. This probe is applicable in cancer-related research.

TBZ-07 is an anti-angiogenesis and vascular disrupting agent that acts by exhibiting moderate inhibitory cell proliferation activity.

Tetrabenazine Metabolite ((-)-β-HTBZ), a vesicles monoamine transporter 2 (VMAT2) inhibitor, is an active metabolite of Tetrabenazine. Tetrabenazine Metabolite has a high affinity for VMAT2 with a Ki of 13.4 nM. Tetrabenazine Metabolite is often used to study chorea associated with Huntington's disease and other hyperactivity disorders.

NBI-98782 ((+)-α-DHTBZ) is an inhibtior of vesicular monoamine transporter (VMAT2) (Ki: 0.97 nM)

Trans (2,3)-Dihydrotetrabenazine is a Tetrabenazine metabolite, shows inhibition activity on vesicular monoamine transporter (VMAT2).

GJN75561 is a VMAT2 imaging agent.

(2S,3S,11bR)-Dihydrotetrabenazine ((2S,3S,11bR)-DHTBZ) is a highly selective inhibitor of vesicular monoamine transporter 2 (VMAT2) with a Ki value of 593 nM. It suppresses the vesicular transport of monoamine neurotransmitters, such as dopamine and serotonin, leading to reduced release into the synaptic cleft. This compound holds potential for research in Huntington's disease and other hyperkinetic movement disorders.

5'-O-DMT-Bz-Rc is a modified nucleoside used in the synthesis of DNA or RNA.

5'-O-DMT-Bz-rA, a nucleoside, consists of a ribose sugar attached to an adenine base with a benzoyl protecting group at the N6 position and a dimethoxytrityl (DMT) protecting group at the 5' position of the ribose.

5-hydroxy Thiabendazole (5-OH TBZ) is a major metabolite of the anthelmintic thiabendazole . Unlike thiabendazole, 5-OH TBZ has no effect on the growth of third-stage A. caninum larvae.