taurocholic acid

Taurocholic acid (N-Choloyltaurine) is a bile acid involved in fat emulsification, possessing notable biological and immunomodulatory activities. It can inhibit bile duct injury induced by hepatic artery ligation by upregulating VEGF-A expression and protect cholangiocytes from TNF-α-induced damage via a PI3K-mediated pathway, and is commonly used to induce pancreatitis models.

3-Sulfo-taurocholic acid disodium salt (3-Sulfocholyl Taurine disodium salt) is a derivative of bile acid taurocholic acid.

Sodium taurocholate is a biologically active compound that can inhibit bile duct injury induced by hepatic artery ligation by upregulating VEGF-A expression. It also exhibits immunomodulatory effects and can be used to induce pancreatitis models.

Taurocholic acid sodium salt hydrate is a bile acid sodium salt hydrate that participates in fat emulsification and can be used to establish pancreatitis models.

Taurocholic Acid-D4 Sodium is a deuterium-labelled compound of Taurocholic Acid (TMSM-2592), which can be used for isotopic tracing. Taurocholic Acid is an immunomodulatory bile acid that plays an essential role in the digestion and absorption of fats and steroids in the intestine and liver.

Taurocholic acid-D4 is the deuterated form of Taurocholic acid. Taurocholic acid (TN2259) (N-Choloyltaurine) is a bile acid involved in the emulsification of fats.

Taurocholic Acid-3-O-Glucuronide (Standard) is a reference standard of Taurocholic Acid-3-O-Glucuronide intended for quantitative analysis, quality control, and related biochemical research applications.

Taurocholic Acid-3-Sulfate Sodium Salt (Standard) is a reference standard of Taurocholic Acid-3-Sulfate Sodium Salt intended for quantitative analysis, quality control, and related biochemical research applications.

Taurocholic acid-3-o-glucuronide-D4 (Standard) is a reference standard of Taurocholic acid-3-o-glucuronide-[D4] intended for quantitative analysis, quality control, and related biochemical research applications.

Taurocholic Acid-D4 Sodium (Standard) is a reference standard of Taurocholic Acid-D4 Sodium intended for quantitative analysis, quality control, and related biochemical research applications. Taurocholic Acid-d4 Sodium is a deuterium-labelled compound of Taurocholic Acid, which can be used for isotopic tracing.Taurocholic Acid is an immunomodulatory bile acid that plays an essential role in the digestion and absorption of fats and steroids in the intestine and liver.

Taurocholic Acid-[D4]-3-Sulfate Sodium Salt (Standard) is a reference standard of Taurocholic Acid-[D4]-3-Sulfate Sodium Salt intended for quantitative analysis, quality control, and related biochemical research applications.

Rapavir (JH-B10) is a selective and potent inhibitor of sodium taurocholate co-transporting polypeptide (NTCP), with an IC50 value of 1.8 nM for taurocholic acid-d4 (TCA-d4) uptake. It exhibits antiviral activity against HBV infection by directly binding to NTCP and preventing the virus from entering cells. Rapavir is promising for HBV infection research.

Isodeoxycholic Acid is a bile acid that is formed via epimerization of deoxycholic acid by intestinal bacteria. It has a greater critical micelle concentration than DCA, indicating reduced detergent activity, and is less active than DCA in inhibiting growth in a panel of seven gut commensal bacteria species. Isodeoxycholic Acid(0.1%) inhibits spore germination induced by taurocholic acid in several C. difficile strains, as well as decreases the cytotoxicity of C. difficile culture supernatants to Vero cells. Plasma levels of isodeoxycholic acid are decreased in a rat model of high-fat diet-induced obesity compared with rats fed a normal diet.

Tauroursocholic acid (TUCA) is the taurine-conjugated derivative of ursocholic acid and serves as the 7β-hydroxy epimer of taurocholic acid (TCA). Unlike TCA, TUCA does not inhibit HMG-CoA reductase or the cytochrome P450 (CYP) isoform CYP7A1, also known as cholesterol 7α-hydroxylase. Elevated bile levels of TUCA are observed in patients with biliary tract cancer compared to those with benign biliary conditions.

Tauro-3α,6α,7α,12α-tetrahydroxy bile acid is a type of taurocholic acid.