srpk

Srpk1-IN-1 (compound 12) serves as a potent inhibitor of SRPK 1, demonstrating an IC 50 value of 0.3 nM [1].

SRPKIN-1 is a covalent and irreversible inhibitor of SRPK1 2 (IC50s: 35.6 and 98 nM, respectively).

SPHINX is a new generation inhibitor of SPRK1

SRPIN340 (SRPK inhibitor), a serine arginine-rich protein kinase (SRPK)-specific inhibitor, is potent for SRPK1 (IC50 = 0.89 uM).

SPHINX31 is a potent inhibitor of serine arginine-rich protein kinase 1 (SRPK1; IC50: 5.9 nM).

MSC-1186 is a potent and highly selective inhibitor targeting the pan-SRPK family, including SRPK1, SRPK2, and SRPK3, with IC 50 values of 2.7 nM, 81 nM, and 0.6 nM, respectively. Its specificity and effectiveness make it suitable for cancer research applications.

Antiangiogenic Agent 5 (Compound 17) exhibits potent anti-angiogenic activity by inhibiting SRPK 1 with an IC50 of 1.3 nM [1].