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serine peptidase inhibitor, kazal type 2

" in TargetMol Product Catalog
  • Recombinant Protein
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SPINK2 Protein, Human, Recombinant (hFc)
SPINK2, serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor), HUSI-II
TMPY-00163
Human serine proteinase inhibitor Kazal-type 2 (SPINK2) functions as a trypsin acrosin inhibitor and is synthesized mainly in the testis and seminal vesicle where its activity is engaged in fertility. The SPINK2 protein contains a typical Kazal domain composed by six cysteine residues forming three disulfide bridges. The expression of SPINK2 is closely related to cancer such as lymphomas, in that a high transcript level of SPINK2 in patients with primary cutaneous follicle center cell lymphomas have better prognosis with lower mortality. SPINK2 is necessary to neutralize proteases during their cellular transit toward the acrosome and that its deficiency induces a pathological continuum ranging from oligoasthenoteratozoospermia in heterozygotes to azoospermia in homozygotes.
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7-10 days
Size
QTY
SPR-compatible buffer
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SPINK2 Protein, Mouse, Recombinant (His & Myc)
Spink2, Serine protease inhibitor Kazal-type 2
TMPH-02898
Expression system: E. coli
Length: 17-86, Full Length of Mature Protein
Activity: Not Tested
  • Inquiry Price
20 days
Size
QTY