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seco duba

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  • Inhibitors & Agonists
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Seco-DUBA
SecoDUBA
T386111227961-59-2
Seco-DUBA is an anticancer DNA alkylating agent and prodrug of DUBA, which can be used as a cytotoxic antibody-drug conjugate (ADC). It has an IC50 of 18 nM against KB and 430 pM against SK-OV-3, and can be converted into DUBA with higher stability and activity in vivo.
  • $977
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Seco-DUBA hydrochloride
T392131795733-93-5
Seco-DUBA hydrochloride, a toxin used in the antibody-drug conjugate (ADC) SYD985.
  • $1,520
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Vc-seco-DUBA
T183621345681-58-4
Vc-seco-DUBA is a drug-linker conjugate for ADC with potent antitumor activity by using DUBA (DNA alkylating agent), linked via the ADC linker Vc-seco[1].
  • $1,980
7-10 days
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Desmethyl Vc-seco-DUBA
T82577
Desmethyl Vc-seco-DUBA, a compound comprising a cleavable ADC linker (Desmethyl Vc-seco) and a DNA alkylating agent (DUBA), is utilized in the synthesis of antibody-drug conjugates (ADCs) [1].
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