schisandra

Polysacharide of Schisandra chinensis is a natural product that can be used in related research in the field of life sciences. Its product number is TN8887.

Schisandrathera D, a lignan sourced from Schisandra sphenanthera [1], exhibits hepatoprotective effects.

Schisantherin A (Wuweizi ester-A) is a dibenzocyclooctadiene lignan isolated from the fruit of Schisandra sphenanthera, has been used as an antitussive, tonic, and sedative agent.

Schisandrin A, a primary active component extracted from the traditional Eastern medicine Schisandra chinensis, inhibits CYP3A activity, with an IC50 of 6.60 μM and a Ki of 5.83 μM.

Schisandrin (Wuweizi alcohol-A) is a compound with anti-asthmatic, anti-cancer, and anti-inflammatory effects.

Schisandrin C (Wuweizisu-C) is a phytochemical lignan isolated from Schizandra chinensis Baill; shows anticancer-effects in human leukemia U937 cells.

1. Heteroclitin D can inhibit L-type calcium channels. 2. Heteroclitin D might be a valuable antitumor promoter or chemopreventor.

Angeloylisogomisin O, a dibenzocyclooctadiene lignan, is isolated from the aerial parts of Schisandra propinqua var. propinqua.

Schisandrin B (Schisandrin B (Sch B)) has an antioxidant effect on rodent liver and heart.

Macelignan (Anwuligan) is a lignan isolated from nutmeg with antimicrobial and anticariogenic activity against Streptococcus mutans and other streptococcus species.

Gomisin J is a natural product and have vasodilatory activity. Gomisin J suppresses lipid accumulation by regulating the expression of lipogenic and lipolytic enzymes and inflammatory molecules through activation of AMPK, LKB1 and Ca2+ calmodulin-dependent protein kinase II and inhibition of fetuin-A in HepG2 cells.

β-Chamigrenal has anti-inflammatory activity, it has inhibitory effects on lipopolysaccharide-induced nitric oxide and prostaglandin E2 production in RAW 264.7 macrophages. Chamigrenal shows platelet-activating factor antagonistic activity and the IC(50)

Schisantherin E is a natural lignan isolated from Schisandra chinensis. Schisandra chinensis has antioxidant, hepatoprotective, sedative, anticancer, anti-SARS and anti-inflammatory activities.

1. Schisandrol B (Besigomsin) may exert neuroprotective effects by attenuating the microglia-mediated neuroinflammatory response via inhibiting the TLR4-mediated NF-κB and MAPKs signaling pathways. 2. Schisandrol B has anti-inflammatory property, potentially result from the inhibition of COX-2, iNOS, IL-6, TNF-α and NO through the down-regulation of RIP2 and NF-κB activation. 3. Schisandrol B induces marked protective effects against hepatic and renal injury induced by CCl(4) exposure through differential regulation of the MAPK signal transduction pathway. 4. Schisandrol B significantly inhibits cell proliferation in a dose-dependent manner, due to cell cycle arrest in the G1 phase with the downregulation of cyclin D1 expression and Retinoblastoma (RB) phosphorylation.

1. Schisantherin B (Schizantherin-B) shows good effect in lowering the serum glutamic-pyruvic transaminase level of the patients suffering from chronic virus hepatitis.

1. Schisanhenol (Schizanhenol) can protect against adriamycin induced heart mitochondrial toxicity. 2. Schisanhenol has antioxidative effect on human LDL oxidation, may be through scavenging free radicals. 3. Schisanhenol has anti-apoptosis effect on BACSs, may be related to its inhibition of ROS generation.

Kadsuralignan A (compound 1), a dibenzocyclooctadiene lignan extracted from the leaves and stems of Schisandra lancifolia, exhibits anti-HIV activity, with an effective concentration (EC50) of 2.23 μg mL [1].

Yunnankadsurin B, a dibenzocyclooctene-type lignan, is derived from the stems of Schisandra chinensis (Kadsura) [1].

Schisantherin S, a dibenzocyclooctene-type lignan, is extracted from the stems of Schisandra chinensis (Kadsura) [1].

Schisanligone B, a lignan, has been isolated from the seeds of Schisandra chinensis [1].

Schisandrin C, a lignan extracted from the fruit of Schisandra chinensis, exhibits antihepatitis, antitumor, and anti-HIV-1 activities [1].

Schibitubin I, a lignin with neuroprotective activity, can be isolated from the fruits of Schisandra bicolor var. tuberculata [1].

Schisandrin E (compound 5), a lignan extractible from Schisandra chinensis [1], exhibits pharmacological properties.

Rubriflorin B, a lignan derived from Schisandra rubriflora [1], can be isolated for various applications.