scapularis

Afoxolaner is an isoxazoline insecticide/acaricide against Ixodes scapularis in dogs. Afoxolaner acts on the insect GABA and glutamate receptors, inhibiting GABA & glutamate-regulated uptake of chloride ions, resulting in excess neuronal stimulation and death of the arthropod.

γ-Cyhalothrin is an orally active synthetic type II pyrethroid insecticide capable of penetrating the blood-brain barrier. It is the insecticidally active enantiomer of λ-Cyhalothrin. γ-Cyhalothrin disrupts voltage-gated sodium channels, causing reduced spontaneous activity and salivation in rats. It exhibits toxic effects on aquatic invertebrates and fish, affecting aquatic communities, and inhibits host-seeking behaviors of Ixodes scapularis nymphs in residential turfgrass areas. γ-Cyhalothrin is utilized in research related to insect control.

Afoxolaner (Standard) is the standard substance of Afoxolaner, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Afoxolaner is an isoxazoline insecticide/acaricide against Ixodes scapularis in dogs. Afoxolaner acts on the insect GABA and glutamate receptors, inhibiting GABA & glutamate-regulated uptake of chloride ions, resulting in excess neuronal stimulation and death of the arthropod.