saxagliptin

Saxagliptin (BMS-477118) is a selective, reversible DPP4 inhibitor with an IC50 of 26 nM.

Saxagliptin is a new oral hypoglycemic of the new dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. Saxagliptin is a competitive DPP4 inhibitor that slows the inactivation of the incretin hormones and reducing fasting and postprandial glucose conce

Saxagliptin hydrate (Onglyza hydrate) is a selective and reversible DPP4 inhibitor (IC50: 26 nM; Ki: 1.3 nM).

5-Hydroxy saxagliptin hydrochloride is the active metabolite of Saxagliptin and serves as a potent and selective DPP-4 inhibitor. The Ki values for 5-Hydroxy saxagliptin hydrochloride are 2.6 nM in humans and 2.9 nM in cynomolgus monkeys. This compound is applicable in the research of type 2 diabetes.

Saxagliptin hydrochloride (Standard) is a reference standard for research and analysis in studies involving Saxagliptin hydrochloride. Saxagliptin is a new oral hypoglycemic of the new dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. Saxagliptin is a competitive DPP4 inhibitor that slows the inactivation of the incretin hormones and reducing fasting and postprandial glucose concentrations in a glucose-dependent manner in patients with type 2 diabetes mellitus.

5-Hydroxy Saxagliptin-13C-D2 hydrochloride the 13C and deuterated compound of 5-Hydroxy Saxagliptin hydrochloride. 5-Hydroxy Saxagliptin hydrochloride has a CAS number of 841302-24-7.

5-Hydroxy saxagliptin-13C,d2-2 hydrochloride is a 13C and deuterium-labeled version of 5-Hydroxy saxagliptin hydrochloride. The latter is an active metabolite of Saxagliptin that functions as a potent and selective DPP-4 inhibitor. It exhibits Ki values of 2.6 nM in humans and 2.9 nM in cynomolgus monkeys. This compound is utilized in the study of type 2 diabetes.