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rock1 (p160rock)

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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
Y-27632 dihydrochloride
Y-27632 2HCl
T1725129830-38-2
Y-27632 dihydrochloride (Y-27632 2HCl) is an orally potent, ATP-competitive inhibitor of ROCK-I and ROCK-II. Y-27632 dihydrochloride also inhibits isolation-induced apoptosis in mouse prostate stem or progenitor cells.
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TargetMol | Inhibitor Hot
fasudil dihydrochloride
T61382203911-27-7
Fasudil dihydrochloride, also known as HA-1077 and AT877, is a nonspecific inhibitor of RhoA ROCK. It exhibits inhibitory effects on protein kinases, including ROCK1 with a Ki value of 0.33 μM, as well as ROCK2, PKA, PKC, and PKG with IC 50 values of 0.158 μM, 4.58 μM, 12.30 μM, and 1.650 μM, respectively. Additionally, Fasudil dihydrochloride demonstrates potent Ca 2+ channel blocking activity and acts as a vasodilator [1] [2] [3].
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1-2 weeks
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fasudil hydrochloride semihydrate
T64582
Fasudil hydrochloride semihydrate is a useful organic compound for research related to life sciences and the catalog number is T64582.
    7-10 days
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    fasudil hydrochloride hydrate
    T70108186694-02-0
    Fasudil hydrochloride hydrate is an HCl salt of Fasudil -- a Rho-kinase (ROCK) inhibitor that has been shown to be effective in hindering the development of mature Cerebral Cavernous Malformation (CCM) lesions as well as reducing portal venous pressure in cirrhotic rats.
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    1-2 weeks
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