retinyl

Retinyl acetate (Vitamin A acetate) is a group of unsaturated nutritional hydrocarbons, that contains retinal, retinol, retinoic acid, and several provitamins A carotenoids, among which beta-carotene is the most important.

Retinyl palmitate (Vitamin A palmitate) is a naturally-occurring phenyl analogue of retinol, with potential antineoplastic and chemopreventive activities.

Retinyl-β-D-glucoside, a biologically active metabolite of vitamin A, naturally occurs in fish and mammals.

13-cis-Retinyl acetate (13-cis-Retinol acetate; 13-cis-Vitamin A acetate), a 13-cis isomer of Retinyl acetate, functions as an active metabolite of vitamin A [1].

Retinyl palmitate-d4 is a deuterium-labeled form of Retinyl palmitate. Retinyl palmitate, an ester of retinol, serves as the primary form of vitamin A in the epidermis. It is extensively used in pharmaceutical and cosmetic research.

Retinyl oleate is A fatty acid ester formed from oleic acid and all-trans retinol (vitamin A) that is used in the preparation of oily acne treatment preparations.

Retinyl formyl aspartamate is a novel synthesized retinol derivative with higher photostability.

Retinyl acetate-D4 is the deuterated form of Retinyl acetate. Retinyl acetate (T0685) is a synthetic acetate ester derived from retinol, possessing potential antineoplastic and chemopreventive properties.

Retinyl acetate (Standard) is the standard substance of Retinyl acetate, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Retinyl acetate (Vitamin A acetate) is a group of unsaturated nutritional hydrocarbons, that contains retinal, retinol, retinoic acid, and several provitamins A carotenoids, among which beta-carotene is the most important.

Retinyl palmitate (Standard) is the standard substance of Retinyl palmitate, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Retinyl palmitate (Vitamin A palmitate) is a naturally-occurring phenyl analogue of retinol, with potential antineoplastic and chemopreventive activities.

Retinyl Acetate-D4 (Standard) is a reference standard of Retinyl Acetate-D4 intended for quantitative analysis, quality control, and related biochemical research applications. Retinyl acetate-d4 is the deuterated form of Retinyl acetate. Retinyl acetate is a synthetic acetate ester derived from retinol, possessing potential antineoplastic and chemopreventive properties.

ALK-001 is a vitamin A (TMSM-2031) analog, which may be used to treat Stargardt disease.

5,6-Epoxyretinyl palmitate is a primary photodecomposition product of Retinyl palmitate when exposed to UVA light. It exhibits photocytotoxicity, leading to significant DNA single-strand breaks, DNA damage, and chromosomal mutations under illuminated conditions.

N6-(Retinylidene)lysine is a protein.

LRAT-IN-1 (compound 1) is an inhibitor of lecithin retinol acyltransferase (LRAT) with an IC50 value of 21.1 μM. This compound works by inhibiting the esterification of retinol to form retinyl esters, thereby increasing the availability of retinol in the skin to deliver anti-aging benefits. LRAT-IN-1 is under investigation for its potential use as an anti-aging ingredient in cosmetics.

EYE-003 is an orally active RPE65 inhibitor with an IC50 value of 102 nM. It regulates the visual cycle in mice by decreasing the synthesis of 11-cis-Retinal (11cRAL) and increasing all-trans-retinyl esters (atREs). EYE-003 also inhibits dark-adapted electroretinogram (ERG) b-wave amplitudes and provides protection against retinal degeneration in Abca4⁻/⁻Rdh8⁻/⁻ mice by dose-dependently reducing retinal autofluorescent spots and preserving outer nuclear layer (ONL) thickness. EYE-003 is applicable for researching retinal disorders related to the visual cycle, such as Stargardt disease type 1 (STGD1).

EYE-002 is an RPE65 inhibitor with an IC50 of 69 nM. It enhances the recovery of dark-adapted electroretinogram (ERG) a-/b-wave amplitudes in mice. EYE-002 regulates the visual cycle in mice by reducing 11-cisretinal (11cRAL) synthesis and increasing all-trans-retinyl esters (atREs). It offers protective effects against light-induced retinal damage in mice. EYE-002 is valuable for research on retinal disorders related to the visual cycle, such as Stargardt disease type 1 (STGD1).

11-cis Retinol is an isomer of vitamin A, serving as an agonist for red rod optochromin and an inverse agonist for red cone optochromin.

9-cis-Vitamin A palmitate (9-cis-Retinyl palmitate) is a 9-cis isomer derived from the interaction of vitamin A palmitate in corn flakes, exhibiting 26% of the biological activity of the all-trans-vitamin A palmitate, the most biologically active form of vitamin A.

13-cis-Vitamin A palmitate (13-cis-Retinyl palmitate), a derivative of vitamin A palmitate found in corn flakes, is the 13-cis isomer with 75% of the biological activity of the all-trans form, the most active form of vitamin A [1].

Vitamin A-D5 Acetate is a deuterated compound of Vitamin A Acetate. Vitamin A Acetate (T0685) has a CAS number of 127-47-9. Vitamin A is a group of unsaturated nutritional hydrocarbons, that contains retinal, retinol, retinoic acid, and several provitamins A carotenoids, among which beta-carotene is the most important.

Myeloperoxidase, Human Neutrophil, is a peroxidase enzyme that acts as a potent antimicrobial agent by catalyzing the oxidation of chloride ions dependent on H2O2, producing hypochlorous acid. It also facilitates the degradation of N-retinylidene-N-retinyl-ethanolamine [a toxic form of retinal lipofuscin], and induces lysosomal stress and cell death. This enzyme is useful for research in inflammation and infection.