Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty
Filter
Applied FilterClear all
TargetMol | Tags By Target
  • Retinoid Receptor
    (37)
  • Autophagy
    (23)
  • Apoptosis
    (9)
  • ROR
    (7)
  • Cytochromes P450
    (2)
  • Endogenous Metabolite
    (2)
  • PPAR
    (2)
  • Phospholipase
    (2)
  • RAR/RXR 
    (2)
  • Others
    (26)
Filter
Search Result
Results for "

retinoic acid receptor

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    68
    TargetMol | Inhibitors_Agonists
  • Natural Products
    5
    TargetMol | Natural_Products
  • Recombinant Protein
    11
    TargetMol | Recombinant_Protein
  • Isotope Products
    1
    TargetMol | Isotope_Products
  • Antibody Products
    3
    TargetMol | Antibody_Products
BMS493
BMS-493
T14689215030-90-3In house
BMS493 is an inverse agonist of the pan-retinoic acid receptor (RAR) that inhibits retinoic acid-induced differentiation, enhances the interaction of nuclear co-inhibitors with RARs, attenuates RA signaling, potentiates TPP-induced toxicity, and inhibits the increase in phospholipase A2 activity.
  • Inquiry Price
7-10 days
Size
QTY
ER 50891
T22767187400-85-7In house
ER-50891 is a potent retinoic acid receptor alpha (RARα) antagonist. er-50891 reduces the inhibitory effect of allosteric retinoic acid and restores osteoblast differentiation induced by bone morphogenetic protein 2.
  • Inquiry Price
8-10weeks
Size
QTY
ML 209
T375871334526-14-5In house
ML-209 is an antagonist of retinoic acid receptor-related orphan receptor γt (RORγt; IC50= 1.1 μM in a reporter assay).1It inhibits RORγt-induced transcription in HEK293T cells expressing the human receptor (IC50= 300 nM). ML-209 inhibits RORγt-dependent differentiation of isolated na?ve cord blood human CD4+T cells into Th17 T helper cells.
  • Inquiry Price
6-8 weeks
Size
QTY
KCL-286
T785751952276-71-9In house
KCL-286 is an orally available and potent retinoic acid receptor beta agonist for the amelioration of spinal cord injury (SCI).
  • Inquiry Price
8-10weeks
Size
QTY
Oxybenzone
KAHSCREEN BZ-3, Benzophenone 3, Eusolex 4360, Escalol 567
T0499131-57-7
Oxybenzone is a UV filter commonly used in tanning and skin protection agents. It is a derivative of benzophenone and is used as an endocrine disrupting chemical that penetrates the placental and blood-brain barriers. It impairs autophagy, alters epigenetic status and disrupts vitamin X-like receptor signaling in apoptotic neuronal cells.
  • Inquiry Price
Size
QTY
Retinoic acid
Vitamin A acid, Tretinoin, ATRA, all-trans-Retinoic acid
T1051302-79-4
Retinoic acid (Tretinoin), a metabolite of vitamin A, is a natural agonist of the retinoic acid receptor RAR and inhibits RARα β γ (IC50=14 nM). Retinoic acid induces cellular differentiation, reduces cellular proliferation, and inhibits tumorigenesis.
  • Inquiry Price
Size
QTY
Adapalene
CD271
T1093106685-40-9
Adapalene (CD271) is a dual RAR and RXR agonist, utilized in the treatment of skin conditions.
  • Inquiry Price
Size
QTY
Polyinosinic-polycytidylic acid sodium
Poly(I:C) sodium
T1251642424-50-0
Polyinosinic-polycytidylic acid sodium (Poly(I:C) sodium) is a synthetic analog of double-stranded RNA and an agonist of toll-like receptor 3 (TLR3) and retinoic acid inducible gene I (RIG-I)-like receptors (RIG-I and MDA5).
  • Inquiry Price
Size
QTY
Acitretin
Ro 10-1670, Etretin
T133055079-83-9
Acitretin (Ro 10-1670) is a second-generation systemic retinoid used in the treatment of psoriasis.
  • Inquiry Price
Size
QTY
Isotretinoin
13-cis-Retinoic acid
T16114759-48-2
Isotretinoin (13-cis-Retinoic acid) binds to and activates nuclear retinoic acid receptors (RARs), which act as transcription factors that promote cell differentiation and apoptosis. This naturally occurring retinoic acid has potential antineoplastic activity, exhibits immunomodulatory and anti-inflammatory responses, and inhibits ornithine decarboxylase, thereby decreasing polyamine synthesis and keratinization.
  • Inquiry Price
Size
QTY
Bexarotene
Targretin, Ro 26-4455, LGD1069
T6410153559-49-0
Bexarotene (LGD1069) is a retinoid analogue that is used to treat the skin manifestations of cutaneous T cell lymphoma (CTCL).
  • Inquiry Price
Size
QTY
Tamibarotene
NSC 608000, Am 80, Amnolake
T669494497-51-5
Tamibarotene (Amnolake) is an orally active, synthetic retinoid, developed to overcome all-trans retinoic acid (ATRA) resistance, with potential antineoplastic activity.
  • Inquiry Price
Size
QTY
Magnolol
NSC 293099, 5,5'-Diallyl-2,2'-biphenyldiol
T3000528-43-8
Magnolol (5,5'-Diallyl-2,2'-biphenyldiol) is a dual agonist of RXRα( EC50=10.4 μM) and PPARγ(EC50=17.7 μM). It blocks TNF-α-induced NF-KB activation.
  • Inquiry Price
Size
QTY
AR7
T395580306-38-3
AR7 is a retinoic acid receptor α (RARα) antagonist.
  • Inquiry Price
Size
QTY
GSK2981278
ROR gama modulator 1
T40501474110-21-8
GSK2981278 (ROR gama modulator 1) is a highly potent and selective inverse agonist of retinoic acid receptor-related orphan receptor gamma (ROR gamma).
  • Inquiry Price
Size
QTY
SR1078
SR 1078
T45941246525-60-9
SR1078 is an agonist of retinoic acid receptor-related orphan receptor (ROR)α γ.
  • Inquiry Price
Size
QTY
Tazarotene
Tazorac, AGN 190168, Zorac
T6696118292-40-3
Tazarotene (Zorac) is a synthetic, topical retinoid. Tazarotene induces the expression of tazarotene-induced gene 3 (TIG3), a tumor suppressor gene. In psoriasis, tazarotene normalizes abnormal keratinocyte differentiation and reduces their hyperproliferation.
  • Inquiry Price
Size
QTY
TargetMol | Inhibitor Sale
BMS453
BMS 453, BMS-189453
T21714166977-43-1
BMS453 (BMS-189453), a synthetic retinoid, is a potent and selective agonist of RARβ and a potent testicular toxin. BMS453 inhibits breast cell growth predominantly through the induction of active TGFβ.
  • Inquiry Price
10-14 weeks
Size
QTY
TargetMol | Inhibitor Sale
Tazarotenic acid
AGN-190299
T7894118292-41-4
Tazarotenic acid (AGN-190299) is a retinoid prodrug which is converted to its active form
  • Inquiry Price
Size
QTY
TargetMol | Inhibitor Sale
Adapalene sodium salt
CD 271 sodium salt
T10246911110-93-5
Adapalene (CD 271; Differin) sodium salt is a synthetic retinoid and a Retinoic acid receptor agonist.
  • Inquiry Price
6-8 weeks
Size
QTY
FM26
T113082407981-35-3
FM26 has a distinct isoxazole chemotype and effectively reduces IL-17a mRNA production in EL4 cells. FM26 is a potent and allosteric retinoic acid receptor-related orphan receptor γt (RORγt) inverse agonists with an IC50 of 264 nM.
  • Inquiry Price
8-10 weeks
Size
QTY
LG-100064
T11844153559-46-7
LG-100064 is an agonist of retinoid-X-receptor (RXR)(EC50s of 330 nM, 200 nM, and 260 nM for RXRα, RXRβ and RXRγ)
  • Inquiry Price
Size
QTY
Liarozole
R75251 dihydrochloride
T11847L115575-11-6
Liarozole (R75251 dihydrochloride) is a cytochrome P450 (CYP450) dependent inhibitor, orally active, it also a potent inhibitor of estrogen (via inhibition of aromatase) and testicular androgen synthesis (inhibition of 17 ,20-lyase).Liarozole dihydrochloride is an imidazole derivative; it is being investigated as a non-hormonal agent in prostate cancer and in the treatment of various other cancers and skin disorders.
  • Inquiry Price
Size
QTY
ROR agonist-1
T127502361528-74-5
ROR agonist-1 is a potent and orally bioavailable inverse agonist of the retinoic acid receptor-related orphan receptor C2 (RORC2), demonstrating inhibition of IL-17A production from human primary TH17 cells with a pIC50 of 7.5.
  • Inquiry Price
6-8 weeks
Size
QTY