quassinoid

Bruceine A (NSC-31616)(NSC-310616; Dihydrobrusatol) is a natural quassinoid compound extracted from the dried fruits of Brucea javanica (L.); are potential candidates for the treatment of canine babesiosis.

Pasakbumin D is a quassinoid utilized in cancer research.

Dehydrobruceine B, a quassinoid isolated from Brucea javanica, demonstrates a synergistic effect with Cisplatin in inducing apoptosis through the mitochondrial pathway. It enhances the expression of apoptosis-inducing factor (AIF) and Bax while inhibiting Keap1-Nrf2 [1].

Shinjulactone M, a quassinoid extracted from the Ailanthus species of the Simaroubaceae family, serves as an antimalarial (febrifuge) and anthelmintic. It is also explored in the study of chronic bronchitis, epilepsy, and asthma [1].

Bruceine J, a quassinoid naturally derived from the fruits of Br. javanica, exhibits anti-Babesial activity [1].

Bruceine E is isolated from B. javanica seeds with hypoglycemia effects. Bruceine E can be used for studies about acting as an insulin secretagogue.

Yadanzioside A is a quassinoid and terpenoid extracted from Brucea javanica with antipancreatic cancer activity, inhibition of InhA enzyme (Mycobacterium enoyl acyl carrier protein reductase) and potential as an anti-tuberculosis (TB) drug.

Yadanzioside G is a quassinoid and terpenoid extracted from Brucea javanica with antipancreatic cancer activity, inhibition of InhA enzyme (Mycobacterium enoyl acyl carrier protein reductase) and potential as an anti-tuberculosis (TB) drug.

Yadanzioside C is a quassinoid and terpenoid extracted from Brucea javanica that has the potential to inhibit InhA enzyme (Mycobacterium enoyl acyl carrier protein reductase) and to act as an anti-tuberculosis (TB) drug potential.

Yadanzioside F is a quassinoid and terpenoid extracted from the seed of Crowberry (Brucea javanica), which is lethally toxic to mice and has the potential to inhibit the enzyme InhA (Mycobacterium enoyl acyl carrier protein reductase) and to act as an antituberculosis (TB) agent.

Soularubinone is an anti-leukemic quassinoid compound derived from Soulamea tomentosa.