quassinoid

Bruceine E is isolated from B. javanica seeds with hypoglycemia effects. Bruceine E can be used for studies about acting as an insulin secretagogue.

Bruceine A (NSC-31616)(NSC-310616; Dihydrobrusatol) is a natural quassinoid compound extracted from the dried fruits of Brucea javanica (L.); are potential candidates for the treatment of canine babesiosis.

Javanicin C is a type of quassinoid.

Pasakbumin D is a quassinoid utilized in cancer research.

Dehydrobruceine B, a quassinoid isolated from Brucea javanica, demonstrates a synergistic effect with Cisplatin in inducing apoptosis through the mitochondrial pathway. It enhances the expression of apoptosis-inducing factor (AIF) and Bax while inhibiting Keap1-Nrf2 [1].

Shinjulactone M, a quassinoid extracted from the Ailanthus species of the Simaroubaceae family, serves as an antimalarial (febrifuge) and anthelmintic. It is also explored in the study of chronic bronchitis, epilepsy, and asthma [1].

Bruceine J, a quassinoid naturally derived from the fruits of Br. javanica, exhibits anti-Babesial activity [1].

Yadanzioside A is a quassinoid and terpenoid extracted from Brucea javanica with antipancreatic cancer activity, inhibition of InhA enzyme (Mycobacterium enoyl acyl carrier protein reductase) and potential as an anti-tuberculosis (TB) drug.

Yadanzioside G is a quassinoid and terpenoid extracted from Brucea javanica with antipancreatic cancer activity, inhibition of InhA enzyme (Mycobacterium enoyl acyl carrier protein reductase) and potential as an anti-tuberculosis (TB) drug.

Bruceantinoside A is a naturally occurring quassinoid glucoside belonging to the triterpenoid glycoside class, isolated from the fruits of Brucea genus species including Brucea javanica and Brucea antidysenterica. Bruceantinoside A exhibits antileukemic and cytotoxic activities and is employed as a bioactive research compound in cancer biology. Its complex structure and bioactivity make it valuable for mechanistic studies of natural product-derived anticancer agents.

Yadanzioside C is a quassinoid and terpenoid extracted from Brucea javanica that has the potential to inhibit InhA enzyme (Mycobacterium enoyl acyl carrier protein reductase) and to act as an anti-tuberculosis (TB) drug potential.

Yadanzioside F is a quassinoid and terpenoid extracted from the seed of Crowberry (Brucea javanica), which is lethally toxic to mice and has the potential to inhibit the enzyme InhA (Mycobacterium enoyl acyl carrier protein reductase) and to act as an antituberculosis (TB) agent.

Soularubinone is an anti-leukemic quassinoid compound derived from Soulamea tomentosa.

Dehydrobrusatol is a naturally occurring quassinoid derived from the Brucea javanica plant.

Bruceoside D is a quassinoid natural product discovered in Brucea javanica, exhibiting inhibitory activity against HIV replication in the H9 T-lymphoid cell line (IC50 = 3 μM) and demonstrating potential anticancer activity.