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pta-1

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1,7-Bis(4-hydroxyphenyl)hepta-1,4,6-trien-3-one
TN6235149732-52-5
1,7-Bis(4-hydroxyphenyl)hepta-1,4,6-trien-3-one is a natural product for research related to life sciences. The catalog number is TN6235 and the CAS number is 149732-52-5.
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Protosappanin A
PTA
TJS1779102036-28-2
Protosappanin A (PTA) has anti-oxidative nitrative activities on brain immune and neuroinflammation through regulation of CD14 TLR4-dependent IKK IκB NF-κB inflammation signal pathway; it exerts anti-neuroinflammatory effect by inhibiting JAK2-STAT3 pathway in lipopolysaccharide-induced BV2 microglia. Protosappanin A induces immunosuppression of rats heart transplantation targeting T cells in grafts via NF-kappaB pathway. Protosappanin A and protosappanin B have antimicrobial activity, they show both alone activities and resistance reversal effects of amikacin and gentamicin against MRSA. Protosappanin A shows strong effect against HIV-1 IN with an IC50 value of 12.6 uM.
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