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By Target- Apoptosis
- PROTACs(1)
- ROR(1)
- Others(1)
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Results for "
protac parp-1 degrader
" in TargetMol Product Catalog- Inhibitors & Agonists3
- PROTAC Products2
PROTAC PARP1 degrader
T138452369022-68-2
PROTAC PARP1 degrader is a degrader of PARP1 based on the PROTAC technology. PROTAC PARP1 degrader at 10 μM at 24 h inhibits MDA-MB-231 cell line (IC50 of 6.12 μM).
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PP-C8
T74359
PP-C8, a potent and selective PROTAC CDK12-Cyclin K degrader, efficiently induces degradation of CDK12 and Cyclin K, with DC50 values of 416 nM and 412 nM, respectively. This compound exhibits significant synergistic antiproliferative effects when combined with a PARP inhibitor in triple-negative breast cancer (TNBC) [1].
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