pppa

PPPA is a NMDA receptor antagonist.

M7G(3'-OMe-5')pppA(2'-OMe) is an analogue used for mRNA cap synthesis in vitro.

M7GpppApG is a trinucleotide mRNA 5' cap analog utilized for in vitro RNA synthesis [1].

3'Ome-m7GpppAmpG, a trinucleotide cap analogue with a locked nucleic acid (LNA) molecule, demonstrates notable translational efficiency. It serves as a promising tool in molecular biology, applicable in mRNA vaccines and transfection processes, including protein production, gene therapy, and anti-cancer immunization [1].

3'Ome-m7GpppAmpG ammonium, a trinucleotide Cap analogue with a locked nucleic acid (LNA) component, demonstrates substantial translational efficiency. It emerges as a promising tool in molecular biology, applicable in mRNA vaccines and transfection processes including protein production, gene therapy, and anti-cancer immunization [1].

M7GpppAmpG is a trinucleotide 5′ cap analog, exhibiting capping efficiencies of 90% for the produced RNAs [1].

m7GpppAmpG ammonium is a trinucleotide 5′ cap analog with capping efficiencies of 90% for RNAs obtained [1].

Uracil-m7GpppAmpG ammonium, a cap analog, is used for mRNA synthesis.

pppApG serves as an initial substrate for the synthesis of vRNA (viral RNA) and cRNA (complementary RNA), with applications in influenza virus research [1].

pppApA sodium is a linear dinucleotide intermediate involved in the enzymatic production of bacterial signaling nucleotide c-diAMP. It is formed by the linkage of two ATP molecules.

ABP/PPAR modulator 1 is an orally active multi-regulator of FABP and PPAR, exhibiting IC50 values of 0.65 μM for FABP1 and 1.08 μM for FABP4, and EC50 values of 9.19 μM, 2.20 μM, and 1.58 μM for PPARα, PPARγ, and PPARδ, respectively. It demonstrates potent activity against metabolic dysfunction-associated steatohepatitis (MASH). Additionally, ABP/PPAR modulator 1 dose-dependently improves various pathological features of fatty liver in a WD + Carbon tetrachloride-induced MASH mouse model.

Guanosine 5'-triphosphate-5'-adenosine, known as a 5′ cap analog, serves as a fluorescent substrate analog.

N7-Methylguanosine-5'-triphosphate-5'-adenosine (m7GpppA) is a dinucleotide cap analog employed in the process of in vitro RNA transcription.