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plx 7683.

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  • Inhibitors & Agonists
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cis-Epoxysuccinic acid
T7192116533-72-5
Cis-Epoxysuccinic acid, a succinate receptor (SUCNR1 GPR91) agonist, regulates cardiovascular system research by inhibiting cAMP levels with an EC50 value of 2.7 µM.
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6-8 weeks
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PLX7683
T703081652573-86-8
PLX7683 is a paradox breaker. Paradox breakers overcame several known mechanisms of resistance to first-generation RAF inhibitors. Dissociating MAPK pathway inhibition from paradoxical activation might yield both improved safety and more durable efficacy than first-generation RAF inhibitors
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6-8 weeks
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