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Results for "
pi5p4k
" in TargetMol Product Catalog- Inhibitors & Agonists9
PI5P4K-β-IN-2
T81464
PI5P4K-β-IN-2 (compound d5) is a potent inhibitor of the PI5P4K-β enzyme with an IC50 value of 0.35 μM and exhibits antitumor activity.
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PI5P4K-β-IN-1
T81465332407-28-0
PI5P4K-β-IN-1 (compound vs1) is a potent PI5P4K-β inhibitor with an IC50 of 0.80 μM [1].
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PI5P4Ks-IN-2
T720322766854-03-7In house
PI5P4Ks-IN-2 is an inhibitor of the phosphatidylinositol 5-phosphate 4-kinase PI5P4Kγ. Targeting the PI5P4K isoforms, PI5P4Ks-IN-2 inhibited PI5P4Kα, PI5P4Kβ, PI5P4Kγ, and PI5P4Kγ+, with IC50 values of <4.3, <4.6, 6.2, and 0.32, respectively.
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PI5P4Kα-IN-1
T781782428737-31-7
PI5P4Kα-IN-1 (Compound 13) is a phosphatidylinositol 5-phosphate 4-kinase (PI5P4K) inhibitor with IC50 values of 2 μM for PI5P4Kα and 9.4 μM for PI5P4Kβ, potentially applicable in cancer, metabolic, and immunological disorder studies [1].
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PI5P4Ks-IN-3
T814662471969-07-8
PI5P4Ks-IN-3 (compound 30) is a covalent inhibitor of PI5P4K with inhibition constants (IC50s) of 1.34 μM for PI5P4Kα and 9.9 μM for PI5P4Kβ, but demonstrates weak cellular activity [1].
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PI5P4Ks-IN-1
T60982959560-36-2
PI5P4Ks-IN-1 (compound 7) is an active compound that interacts with PI5P4Kγ[1].
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PI5P4Kγ-IN-1
T871652419358-87-3
PI5P4Kγ-IN-1 (compound 2), a selective PI5P4Kγ inhibitor, facilitates mTORC1 signaling in MCF-7 breast cancer cells and aids in further characterization of PI5P4Kγ within these cells [1].
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THZ-P1-2
T394592058075-45-7
THZ-P1-2 is a selective and potent PI5P4K inhibitor with anti-leukemic activity that acts by disrupting mitochondrial homeostasis and autophagy.THZ-P1-2 induces cell death and mitochondrial damage, and can be used in the study of leukemias.
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CVM-05-002
T861082428738-43-4
CVM-05-002 is an inhibitor of PI5P4K, characterized by IC 50 values of 0.27 μM for PI5P4Kα and 1.7 μM for PI5P4Kβ [1].
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