peptide t

Peptide T, an octapeptide from the V2 region of HIV-1 gp120, is a synthetic octapeptide that potentially acts through competitive inhibition of gp120 binding to the CD4 receptor, as well as binding to vasointestinal peptide receptors and inhibiting cytokine action.

Peptide T acetate is an octapeptide from the V2 region of HIV-1 gp120. Peptide T is a synthetic octapeptide whose possible mechanism of action is the competitive inhibition of gp120 to the CD4 receptor as well as binding to vasointestinal peptide receptors and inhibiting cytokine action

Peptide T (TFA), an octapeptide derived from the V2 region of HIV-1 gp120, functions as a ligand for the CD4 receptor, thereby effectively inhibiting HIV binding to the CD4 receptor.

Peptide T amide is an octapeptide segment of HIV envelope gp120 and is used in AIDS therapy.

Antennapedia Peptide TFA (188842-14-0 free base), a peptide of 16 amino acids, is a member of the family of Cell-penetrating peptides, originally derived from the 60 amino acid long homeodomain of the Drosophila transcription factor Antennapedia.

RNAIII-inhibiting peptide TFA (RNAIII-inhibiting peptide(TFA))(228544-21-6 free base) inhibits S. aureus, effective in the diseases such as cellulitis, keratitis, septic arthritis, osteomylitis and mastitis.

Highly neurotoxic cell-permeable analog of PHF6. Induces aggregation of Tau peptides.

EGFRvIII peptide, a synthetic peptide mirroring the EGFRvIII fusion junction—a tumor-specific, perpetually active EGFR variant missing amino acids 6-273 of the wild-type—binds to HLA-A*0201-positive T2 cells under MHC class I at 25 µg/ml. It enables antigen presentation in dendritic cells from human peripheral blood mononuclear cells (PBMCs), thus activating CD8+ cytotoxic T lymphocytes and prompting IFN-γ production. Administered at 15 µg/animal with the TLR5 agonist flagellin B, EGFRvIII peptide elevates CD8+ T cell numbers, lowers regulatory T cells (Tregs) in the brain, diminishes tumor volume, and extends survival in a GL261 glioblastoma mouse model.

This peptide, a nuclear localization signal DNA tagged to this peptide efficiently translocates into the cell nucleus.

SV40 T-Ag-derived NLS peptide acetate (SV40 T-Ag-derived NLS peptide acetate) is a nuclear localization signal peptide. The DNA labeled with this peptide can be effectively transferred to the nucleus.

Transdermal Peptide TD-1 HCl is a novel peptide for enhanced transdermal drug delivery that facilitates the penetration of the skin barrier by several drugs and large hydrophilic proteins, such as insulin and human growth hormoneb.

OVA-E1 peptide TFA activates the p38 and JNK cascades similarly in mutant and wild-type thymocytes.

Polymyxin B nonapeptide TFA (catalog number T64687) is a valuable organic compound for life sciences research.

Akt SKG Substrate Peptide TFA is a synthetic peptide specifically designed as a substrate for Akt PKB and is not phosphorylated by p70S6K or MAPK1 [1].

Autocamtide-2-related inhibitory peptide (TFA) is a highly specific and potent CaMKII inhibitor with an IC50 value of 40 nM.

TAT peptide (TFA), a cell-penetrating peptide (GRKKRRQRRRPQ) originating from HIV-1's trans-activating transcriptional activator (Tat), facilitates intracellular delivery [1] [2].

Dynamin Inhibitory Peptide TFA competitively inhibits the binding of dynamin to amphiphysin, effectively preventing endocytosis. Additionally, this compound impedes the dopamine D3's influence on GABA A receptors [1].

PDZ1 Domain Inhibitor Peptide TFA, a cyclic peptide featuring a β-Ala lactam side chain linker, specifically targets the PDZ1 domains of postsynaptic density protein 95 (PSD-95). It effectively disrupts the GluR6 PSD-95 interaction, competing against the C terminus of GluR6 for the PDZ1 domain with high efficiency [1].

Calcineurin Autoinhibitory Peptide TFA is a selective inhibitor of Ca2+ calmodulin-dependent protein phosphatase (calcineurin), exhibiting an inhibitory concentration (IC50) of approximately 10 μM. This compound has been shown to protect neurons from excitatory neuronal death [1] [2].

[cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic Polypeptide is a potent and selective neuropeptide Y Y5 receptor agonist, exhibiting a binding affinity with an IC50 of 0.24 nM for the hY5 receptor, and significantly stimulates food intake [1].

DAPK Substrate Peptide TFA is a synthetic peptide used as a substrate for the enzyme death-associated protein kinase (DAPK), with a Michaelis constant (Km) of 9 μM [1].

IKKγ NBD Inhibitory Peptide TFA is a specific NF-κB inhibitor that hinders the interaction between the IKKγ NEMO-binding domain (NBD) and IKKα and IKKβ, effectively preventing TNF-α-induced NF-κB activation. It has been demonstrated to significantly suppress inflammation and improve neurological deficits induced by cerebral ischemia [1] [2] [3].

pm26TGF-β1 TFA peptide is a synthetic peptide that emulates a segment of the human TGF-β1 molecule, demonstrating high affinity for the TGF-β1 receptor. It possesses potent anti-inflammatory capabilities while lacking the ability to attract neutrophils [1] [2].

Protein Kinase C (alpha) Peptide (TFA) is a PKC-α-associated peptide functioning as a lipid-dependent serine threonine protein kinase. It plays a pivotal role in regulating several cellular functions such as survival, proliferation, differentiation, migration, and adhesion [1].