panx1

Trovafloxacin, a broad-spectrum quinolone antibiotic, exhibits potent activity against Gram-positive bacteria.

Trovafloxacin mesylate is a fluoroquinolone antibiotic and a dual inhibitor of DNA gyrase and topoisomerase IV, as well as a selective inhibitor of the Pannexin 1 channel (IC50 = 4 μM). With oral bioactivity and cell permeability, Trovafloxacin does not inhibit connexin 43 or PANX2, and is used for antibacterial therapy.

10Panx Acetate is a mimetic inhibitory peptide that readily and reversibly inhibits the panx1 currents.

Trovafloxacin (Standard) is the standard substance of Trovafloxacin, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Trovafloxacin is a broad-spectrum quinolone antibiotic with potent activity against Gram-positive.

Cx43 hemichannel blocker (IC50 ~7 μM). No significant affinity for gap junctions or Panx1 channels. N-terminal transactivator of transcription (TAT) motif promotes membrane permeability and increases inhibitory effect of Gap19. Active in vivo. Brain penet