palmitoylcarnitine

L-Palmitoylcarnitine chloride (Palmitoyl-L-carnitine chloride) is a fatty acid metabolite with antithrombotic properties that protects mice from ischemic stroke by counteracting intracerebral thrombosis in the tMCAO model.L-Palmitoylcarnitine chloride (Palmitoyl-L-carnitine chloride) is a fatty acid metabolite with antithrombotic properties. Palmitoylcarnitine chloride inhibits the Na/K pump in the heart and inhibits FeCl 3-induced arterial thrombosis Attenuates intracerebral thrombosis and inflammation in a mouse model of transient middle cerebral artery occlusion (tMCAO).

L-Palmitoylcarnitine (L-PC) is an important endogenous fatty acid metabolite that inhibits Na/K ATPase activity and potentiates fibrinolytic enzymes and tPA to inhibit thrombosis.

Palmitoylcarnitine (Palmitoyl DL-carnitine) is a mitochondrial fatty acid oxidation intermediate that acts as a surfactant.

L-Palmitoylcarnitine TFA, a long-chain acylcarnitine and fatty acid metabolite, accumulates in the sarcolemma and disrupts the membrane lipid environment during ischemia. It inhibits K ATP channel activity by interacting with Kir6.2 without altering single-channel conductance [1].

Palmitoylcarnitine chloride (Palmitoyl DL-carnitine chloride) is a mitochondrial fatty acid oxidation intermediate that mediates intralipid cardioprotection.Palmitoylcarnitine chloride eliminates colorectal cancer cell survival by depletion of glutathione. induces cancer cell death and regulates the interaction between protein kinase C βII and its receptor RACK1.

L-Palmitoylcarnitine chloride (Standard) is an acylcarnitine involved in fatty acid metabolism, an intermediate in long-chain fatty acid oxidation and participates in mitochondrial energy metabolism. L-Palmitoylcarnitine chloride (Standard) can be used for quantitative analysis, studying metabolic pathways, and diagnosing related diseases.

3-Hydroxypalmitoylcarnitine (Standard) is an acylcarnitine involved in fatty acid metabolism processes, which has been associated with type 2 diabetes and cardiovascular disease. As a standard, it can be used for quantitative analysis, study of metabolic pathways and diagnosis of related diseases.

Palmitoyl carnitine-d3 HCl is a deuterated compound of Palmitoyl carnitine HCl.

Palmitoylcholine is an acyl choline.1It inhibits protein kinase C activity when used at a concentration of 100 μM.2Palmitoylcholine induces hemolysis in rat erythrocytes.3Plasma levels of palmitoylcholine are decreased in female patients with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS).1 1.Germain, A., Barupal, D.K., Levine, S.M., et al.Comprehensive circulatory metabolomics in ME/CFS reveals disrupted metabolism of acyl lipids and steroidsMetabolites10(1)34(2020) 2.Nakadate, T., and Blumberg, P.M.Modulation by palmitoylcarnitine of protein kinase C activationCancer Res.47(24 Pt 1)6537-6542(1987) 3.Cho, K.S., and Proulx, P.Interactions of acyl carnitines and other lysins with erythrocytes and reconstituted erythrocyte lipoproteinsBiochim. Biophys. Acta318(1)50-60(1973)

Palmitoyl-D-carnitine is a long-chain acylcarnitine, an isomer of palmitoyl-L-carnitine , and the D enantiomer of palmitoyl-DL-carnitine . It inhibits carnitine palmitoyltransferase with a Ki value of 2.1 mM for 14C-palmitoylcarnitine synthesis by erythrocyte membranes.

Palmitoyl L-Carnitine-d3 Hydrochloride is a deuterated derivative of Palmitoyl L-carnitine. Palmitoyl L-carnitine is a long-chain acylcarnitine formed from palmitic acid and carnitine, playing a pivotal role in mitochondrial fatty acidβ-oxidation and energy metabolism. Under pathological conditions such as myocardial ischemia, it accumulates within cell membranes. Research indicates that it alters the membrane lipid environment and modulates KATP channels, thereby affecting the electrophysiological properties of myocytes. As a deuterated internal standard, this compound is primarily utilized in mass spectrometry-based (LC-MS/MS) quantitative analysis, leveraging the kinetic isotope effect (KIE) to enhance precision in pharmacokinetic studies.