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  • NUDIX hydrolase
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nudixhydrolase

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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
TH1760
MKB
T678642567914-01-4
TH1760 (MKB) is an inhibitor of NUDIX-type 15 (NUDT15, IC50= 25 nM). TH1760 can sensitize cells to 6-thioguanine by increasing the accumulation of 6-thio- (d) GTP in nucleic acids. TH1760 can enhance the anti-leukemia effect of thiopurine.
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TH5427
T39785L2253744-56-6
TH5427 is a lead NUDT5 inhibitor(MG assay IC50 = 29 nM).
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