ns 2

NS2 (114-121), Influenza, is a fragment derived from the nonstructural protein 2 (NS2) of the influenza virus, serving as an epitope for influenza research and useful for studying CD8+ cytotoxic T lymphocyte (CTL) responses in antiviral immunity.

Reproxalap (NS-2) covalently binds aldehydes including malondialdehyde and 4-hydroxynonenal. Reproxalap is a reactive aldehyde species sequestering agent for the treatment of the dry eye.

Compound 34e (NS2B/NS3-IN-4) is an allosteric inhibitor of the DENV2 and ZIKV NS2B/NS3 proteases, exhibiting IC50 values of 0.69 µM for DENV2 and 1.04 µM for ZIKV NS2B/NS3 proteases [1].

NS2B/NS3-IN-3 (Compd 66) is a Flavivirus NS2B-NS3 protease inhibitor [1].

NS2B/NS3-IN-5 (Compound 25b) is a variant of the DENV2 and ZIKV NS2B/NS3 protease inhibitor with IC50 values of 0.67 μM for ZIKV and 4.38 μM for DENV2.

NS2B/NS3-IN-6 (Compound 1a) is a derivative of the DENV and ZIKV NS2B/NS3 protease inhibitor, exhibiting IC50 values of 2.23 μM for the ZIKV NS2B/NS3 protease and 25.2 μM for the DENV NS2B/NS3 protease.

NS2B/NS3-IN-2 is a potent, covalent inhibitor of dengue virus (DENV) NS2B/NS3 with an IC50 of 6.0 nM and a Ki of 0.66 μM. It significantly increases cell viability and exhibits no cytotoxicity.

NS2B/NS3-IN-7 is a highly potent inhibitor of the Zika virus NS2B-NS3 protease, possessing a Ki value of 2.33 nM. It effectively reduces the number of ZIKV-infected cells.

NS2B/NS3-IN-3 hydrochloride is a Flavivirus NS2B-NS3 protease inhibitor [1].

Compound 11, also known as NS2B-NS3pro-IN-2, functions as an inhibitor of the Zika Virus NS2B-NS3 protease and exhibits antiviral properties at a concentration of 50 μM [1].

NS2B-NS3pro-IN-1, a potent Zika Virus NS2B-NS3 protease inhibitor, exhibits an EC50 of 50 μM and is significant in the ZIKV replication cycle [1].

NS2B/NS3-IN-8, also known as compound MH1, is an inhibitor of the Zika virus NS2B-NS3 protease [1].

Hepatitis Virus C NS3 Protease Inhibitor 2, a peptide inhibitor derived from a product targeting the NS3 protease of the hepatitis C virus (HCV), exhibits inhibitory activity with a Ki value of 41 nM.

HCVNS5B polymerase-IN-2 (Compound 298) is an inhibitor of the Ns5b polymerase. It holds potential for research into the treatment of hepatitis C virus (HCV) infections.

NS5A-IN-2 (Compound 33) is a potent NS5A inhibitor with remarkable efficacy against HCV genotype 1b, increased activity against genotype 3a (GT 3a), and significant metabolic stability [1].

o-Tolidine Sulfone (contains 2,6-Dimethyl isomer) [3,7-Diamino-2,8-dimethyldibenzothiophene sulfone (contains 2,6-Dimethyl isomer)] acts as a pharmaceutical intermediate in the synthesis of various active compounds.

Palmatine chloride an isoquinoline alkaloid, is an important medicinal herbal extract with diverse pharmacological and biological properties.

Eg5 Inhibitor V, trans-24, is a specific and potent Eg5 inhibitor with an IC50 value of 0.65 μM, suitable for use in cancer research.

ZINC03129319 is an inhibitor of dengue virus (DENV) NS2B-NS3 protease.

NS-2710 is a non-selective GABA(A) receptor partial agonist for the study of anxiety disorders.

trans-2-Benzylamino-1-cyclohexanol ,with CAS No. 40571-86-6, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. trans-2-Benzylamino-1-cyclohexanol provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

trans-2-Undecenoic acid ((E)-Undec-2-enoic acid) ((E)-2-Undecenoic acid) is an α,β-unsaturated carboxylic acid characterized by acid dimers.

ARDP0006 is an inhibitor of NS2B-NS3 protease.

Hexyl but-2-enoate (Hexyl trans-2-butenoate) is an enolate with a fruity flavor that is commonly used in flavors and food additives, and can be used as an organic reagent.