norleucine

5-Oxo-L-norleucine-CoA (5-Oxo-L-norleucine-coenzyme A) is a derivative of coenzyme A.

6-Hydroxy-L-norleucine-CoA (6-Hydroxy-L-norleucine-coenzyme A) is a derivative of coenzyme A.

Norleucine-CoA (Norleucine-coenzyme A) is a derivative of coenzyme A.

L-Norleucine ((S)-Norleucine) is an isomer of leucine, specifically affects protein synthesis in skeletal muscle, and has antivirus activity.

2-Aminohexanoic acid (Norleucine) is a non-protein-derived L-amino acid, widely used in biochemical experiments and drug synthesis research.

ABH Hydrochloride is an arginase inhibitor, it enhances both male and female sexual arousal responses.

6-[(3R,4R)-3-(Acetyloxy)-N,4-dimethyl-6-oxo-L-norleucine]cyclosporin A is a useful organic compound for research related to life sciences and the catalog number is T64488.

Cbz-D-norleucine is a useful organic compound for research related to life sciences. The catalog number is T66705 and the CAS number is 15027-14-2.

Dehydrolysylnorleucine is a bioactive chemical.

Lysinenorleucine s a Lysine and hydroxylysine derivatives that can be used for the treatment of malignant and benign tumors.

L-Azidonorleucine hydrochloride, an unnatural amino acid, serves as a substitute for Methionine, and is used for labeling mammalian cell proteins and identifying various methionyl-tRNA synthetase (MetRS) mutants.

Dihydroxylysinonorleucine is a reducible lysine-derived cross-linking agent, utilized in the cross-linking of Collagen.

Hydroxylysinonorleucine is a covalently bound immature collagen fiber cross-linking molecule. It can be isolated from naturally reduced collagen found in rat tail tendons, corneas, and skin. This compound can assemble into complex structures, providing mechanical stability, strength, and toughness to tissues.

6-Diazo-5-oxo-L-nor-Leucine (L-6-Diazo-5-oxonorleucine) is a glutaminase antagonist (Ki: 6 μM) and an antineoplastic antibiotic produced by an unidentified Streptomyces species from Peruvian soil.

JHU395 is an orally-bioavailable prodrug of a lipophilic glutamine antagonist (GA), 6-diazo-5-oxo-L-norleucine (DON). It demonstrates delivery of DON to malignant peripheral nerve sheath tumor (MPNST) both in vitro and in vivo, resulting in significant antitumor activity in MPNST. Additionally, JHU395 exhibits plasma stability.

Leucine dehydrogenase, purified from Bacillus spheroides, catalyzes the oxidative deamination of L-leucine, L-valine, L-isoleucine, L-norvaline, L-alpha-aminobutyrate, and L-norleucine and the reductive amination of their keto analogues [1].

[Nle8] Somatostatin (1-28), a derivative of somatostatin (1-28) with norleucine (Nle) substituting for methionine at position 8, enhances amylase release and elevates cyclic AMP levels in pancreatic acini [1].

[Thr28, Nle31]-Cholecystokinin (25-33) is a bioactive peptide analog of Cholecystokinin (CCK) that functions as both a hormone and neurotransmitter in the gastrointestinal and central nervous systems, playing a role in satiation by inhibiting food intake. Compared to native CCK8, this analog displays enhanced stability in acidic environments and resistance to air oxidation, due to the substitution of Methionine with Threonine at position 28 and Norleucine at position 31. Structurally, it features a gamma-turn at Thr4, followed by a Gly5-separated helical region encompassing the C-terminal residues.

[Nle8] Somatostatin (1-28) TFA is a derivative of somatostatin (1-28) where methionine at position 8 is replaced with norleucine. This compound enhances the release of amylase and increases cyclic AMP in pancreatic acini.