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Search Results for " nociceptive "

20

Compounds

Cat No. Product Name Synonyms Targets
TN6791 Palvanil Hexadecanamide TRP/TRPV Channel
Palvanil (Hexadecanamide) is a fast desensitizing agonist of TRPV1. it may be promising agents in the therapy of IBS since it modulates intestinal motility and reduces visceral pain.
T8249 Hexahydrofarnesyl acetone Phytone Others , Antibacterial
Hexahydrofarnesyl acetone (Phytone) enhanced both the sticky materials production and cell growth, plays some role in the increase of sticky materials and cell growth.
T10466 BAY-1797 P2X Receptor
BAY-1797 is an orally active and selective P2X4 antagonist (IC50: 211 nM against human P2X4) with anti-nociceptive and anti-inflammatory effects. BAY-1797 displays no or very weak activity on the other P2X ion channels.
TN6729 Azadiradione AZD Others
Azadiradione (AZD) (AZD) from the methanolic extract of seeds of Azadirachta indica
T2786 Oxysophocarpine Prostaglandin Receptor
Oxysophocarpine is extracted from Sophra flavescens Ait.
T21543 AP 18 TRP/TRPV Channel
AP-18 is a potent and selective TRPA1 inhibitor. AP-18 inhibits activation of TRPA1 induced by 50 μM Cinnamaldehyde with an IC50 of 3.1 μM and 4.5 μM for human and mouse TRPA1, respectively. AP-18 could reverse complete ...
T9244 σ1 Receptor antagonist-1 Sigma receptor
σ1 Receptor antagonist-1 is a selective sigma 1 receptor antagonist.
T9461 AZ194 Sodium Channel
CRMP2-Ubc9-NaV1.7 inhibitor 194, is a CRMP2-Ubc9-NaV1.7 inhibitor.
T4552 Fursultiamine Diteftin,Judolor,Alinamin F Others
Fursultiamine (Alinamin F) is a disulfide derivative of thiamine, or an allithiamine. It has potential uses in the treatment of vitamin B1 deficiency.
T6S1369 Vitexin Apigenin-8-C-glucoside Antioxidant
1. Vitexin has antinociceptive and antispasmodic activities. 2. Vitexin exhibits a prominent first-pass effect. 3. Vitexin has antioxidant, antimyeloperoxidase, and α-glucosidase inhibitory activities. 4. Vitexin can eit...
T2525 Alosetron hydrochloride Lotronex,GR 68755C,GR 68755,GR 68755X 5-HT Receptor
Alosetron hydrochloride (GR 68755) is the hydrochloride salt form of alosetron, a potent and selective 5-HT3 receptor antagonist. Alosetron blocks the actions of serotonin at 5-HT3 sites in the peripheral nervous system,...
T9132 Emorfazone PH011085 Others
Emorfazone (PH011085) has an anti-nociceptive effect.
T21380 Pravadoline WIN 48098-6,WIN48098-6,WIN-48098-6 Cannabinoid Receptor
Pravadoline (WIN48098-6) is a cannabinoid receptor agonist. Pravadoline inhibited the PGs synthesis in mouse brain and displayed antinociceptive activity in rodents subjected to a variety of thermal, chemical, and mechan...
T30824 Cgp 29030A Cgp29030A,Cgp-29030A Others
CGP 29030A is a new piperazine derivative with analgesic activity and significant inhibitory effect on potentially nociceptive dorsal horn neurons, which can be used to study painful disorders.
T8341 QX 314 QX-314 Others
QX 314 (Lidocaine N-ethyl bromide) is a blocker of non-membrane-permeable,and Inhibits Acid-Induced Activation of Esophageal Nociceptive C Fiber Neurons.
T12632L (S)-Mirtazapine (S)-6-Azamianserin,(S)-Org3770 5-HT Receptor
(S)-Mirtazapine ((S)-Org3770) is the S(+)-enantiomer of Mirtazapine. (S)-Mirtazapine is a selective 5-HT2 receptor antagonist with pro-nociceptive effects and is often used in combination with the R(-)-enantiomer of Mirt...
T7675 Substance P (1-7) 2TFA(68060-49-1(free base)) Others
Substance P (1-7) 2TFA(68060-49-1(free base)) is the major bioactive metabolite formed after proteolytic degradation of the tachykinin substance P (SP),with anti-inflammatory, anti-nociceptive and anti-hyperalgesic effec...
T14384 AZD8797 KAN-0440567,KAND567 CXCR
AZD8797 (KAND567) is an orally available, selective and potent human CX3CR1-converting antagonist with inhibitory effects on CX3CR1 and CXCR2, and potentially protects against SARS-CoV-2-induced neuronal damage, preventi...
T8846 Beta-Escin B-escin,AESCINE Immunology/Inflammation related
beta-Escin is a natural mixture of triterpenoid saponins isolated from horse chestnut (Aesculus hippocastanum) seeds, can be used as a vasoprotective anti-inflammatory, anti-edematous and anti-nociceptive agent.
T19723 AMTB hydrochloride AMTB TRP/TRPV Channel
AMTB hydrochloride (AMTB HCl) is a novel TRPM8 channel blocker and is effective for pain and urinary diseases. AMTB can act on the bladder afferent pathway to attenuate the bladder micturition reflex and nociceptive refl...
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