nerves — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T2S1720	Huperzine B		AChE
	1. Huperzine-B is a efficient inhibitor of human brain AChE. 2. Huperzine-B can enhance ognitive and protect neuro, may be potentially new drug candidates for Alzheimer's disease therapy.		AChE
T21543	AP 18		TRP/TRPV Channel
	AP-18 is a potent and selective TRPA1 inhibitor. AP-18 inhibits activation of TRPA1 induced by 50 μM Cinnamaldehyde with an IC50 of 3.1 μM and 4.5 μM for human and mouse TRPA1, respectively. AP-18 could reverse complete ...		TRP/TRPV Channel
T15358	Funapide	TV 45070,XEN402	Sodium Channel
	Funapide (TV 45070) is a potent Sodium Channel Nav1.7 inhibitor with potential anti-inflammatory activity for the treatment of erythema gangrenosum, musculoskeletal pain, knee osteoarthritis, and postherpetic nerves.		Sodium Channel
T5S1389	Escin IB		5-HT Receptor , NO Synthase
	Escin Ib inhibits gastric emptying, at least in part, mediated by capsaicin-sensitive sensory nerves, to stimulate the synthesis and/or release of dopamine, to act through central dopamine2 receptor, which in turn causes...		5-HT Receptor , NO Synthase
T0217L	(+)-Dropropizine	(+)-Dropropizine	Histamine Receptor
	(+)-Dropropizine can inhibit histamine receptor, anti-allergic, and reduce a cough by modulation of neuropeptides involved in the cough reflex and by interfering with stimulus activation of peripheral endings of sensory ...		Histamine Receptor
T7040	Angiotensin II human	DRVYIHPF,Angiotensin II,Hypertensin II,Ang II	Apoptosis , RAAS
	Angiotensin II human (Ang II) is a biologically active peptide, a vasoconstrictor. Angiotensin II interacts with AT1R and AT2R to regulate blood pressure, stimulate sympathetic nerves, and increase aldosterone biosynthes...		Apoptosis , RAAS
T6805	Choline bitartrate	2,3,4-trihydroxy-4-oxobutanoate,2-hydroxyethyl(trimethyl)azanium	Others , AChR
	Choline bitartrate (2-hydroxyethyl(trimethyl)azanium) is a form of the nutrient choline which is found in foods. Choline is necessary for normal liver and kidney function and a component of the neurotransmitter acetylcho...		Others , AChR
T2196	Fipronil	Fluocyanobenpyrazole,Termidor	P450 , GluCls , GABA Receptor
	Fipronil (Fluocyanobenpyrazole) is a broad-use insecticide that belongs to the phenylpyrazole chemical family. Fipronil is a broad-spectrum insecticide that disrupts the insect central nervous system by blocking GABA-gat...		P450 , GluCls , GABA Receptor
T64812	Collagenase Type I	Collagenase I,Collagenase Type I (From microorganisms)	Others
	Collagenase Type I is a proteolytic enzyme that breaks down the peptide bonds in collagen, the main structural protein of connective tissue. Collagenase has been explored as a potential treatment option to break down her...		Others
T34885	Tinyatoxin	TNX,TTN,TTX
	Tinyatoxin is a neurotoxin that works through vanillin receptors on sensory nerves.
TP1650	Myelin Basic Protein	Myelin Basic Protein MBP
	Myelin basic protein (MBP) is a protein believed to be important in the process of myelination of nerves in the nervous system.
T15449	GW-406381		COX
	GW406381 is a highly selective inhibitor of cyclooxygenase-2 (COX-2). GW406381 also attenuates spontaneous ectopic discharge in the sural nerves of rats following chronic constriction injury.		COX
T38964	Peripheral Myelin P0 Protein (180-199), mouse	Peripheral Myelin P0 Protein (180-199), mouse
	Peripheral Myelin P0 Protein (180-199), derived from mice, is a purified component of the myelin found in the peripheral nerves. This protein serves as a neuritogenic peptide, initiating the growth of neuronal processes.
T70282	Drofenine
	Drofenin is an anticonvulsant. It is an anticholinergic that acts both at the level of the nerves and the muscle fibers (neurotropic musculotropic effect). Drofenin also acts as FIASMA (functional inhibitor of acid sphin...
T80513	YVAD-CHO
	YVAD-CHO is an inhibitor of interleukin-1β converting enzyme (ICE, caspase 1) that has been shown to partially mitigate motoneuron death in mice with lesioned facial nerves [1].
T37435	PACAP-related Peptide (rat) (trifluoroacetate salt)		PACAP
	PACAP-related peptide (PRP) is an endogenous 29-amino acid peptide that belongs to the secretin/glucagon superfamily of peptides, which includes secretin , glucagon , glucagon-like peptide-1 , GLP-2 , and pituitary adeny...		PACAP
T60493	Guaiacol Carbonate
	Guaiacol Carbonate is an expectorant that acts via virtue of a reflex from the stomach by way of the afferent gastric nerves to the medullary centers, then via peripherally again to the respiratory tract[1].
T37953	Sphingomyelins (buttermilk)
	Sphingomyelins (SMs) are bioactive sphingolipids found in mammalian cell membranes.1SMs make up 2-15% of the total organ phospholipid population but are found at higher concentrations in the brain and myelin sheaths surr...
T74645	Eplontersen
	Eplontersen, a triantennary N-acetyl galactosamine (GalNAc3-7a)-conjugated antisense oligonucleotide, targets transthyretin (TTR) mRNA to suppress the synthesis of both variant and wild-type TTR proteins. The accumulatio...