mg(ii) protoporphyrin ix

Mg(II) protoporphyrin IX, essential for chlorophyll synthesis in Chlorella, functions as a negative regulator of nuclear photosynthetic gene expression and is used as a research tool for studying the signaling molecule in plastid-to-nucleus communication.

Mn(Ⅲ) Protoporphyrin IX Chloride (Manganese(Ⅲ) Protoporphyrin IX Chloride) is a metallated derivative of protoporphyrin IX, an experimental MRI relaxation enhancer.

Ni(II) protoporphyrin IX is a metalloporphyrin compound characterized by limited propensity for axial ligation and distortion upon binding to [ferrochelatase].

Protoporphyrin IX disodium, as a radiation sensitizer, enhances the production of ROS and induces DNA damage even under hypoxic conditions. It also acts as a photosensitizer, undergoing direct degradation through photobleaching upon light exposure. This compound accumulates in rat tumor cells following administration of 5-aminolevulinic acid (5-ALA). When activated with a peak wavelength of 405 nm, Protoporphyrin IX disodium selectively improves basal cell carcinoma. It shows promise in pharmacological research of sonodynamic and photodynamic therapy for cancers such as bladder cancer and nodular basal cell carcinoma.

Cu (II) Protoporphyrin IX functions as a negative control for Zn (II) Protoporphyrin, a heme oxygenase inhibitor. Heme oxygenase is involved in tumor cell resistance to chemotherapy and the regulation of free radical formation, inflammation, and vascular repair.

Mn(II) protoporphyrin IX is a potent intravenous paramagnetic magnetic resonance contrast agent, noted for its strong paramagnetic properties.

Protoporphyrin IX (PPIX) is a tetrapyrrole that is a metabolic precursor of heme, cytochrome c, and chlorophyll. Protoporphyrin IX has been shown to improve liver function, promote cellular tissue respiration, improve protein and glucose metabolism, and resist complement binding.

Ga(III)protoporphyrin-IX, a model for interporphyrin interactions in malaria pigment, possesses potent antibacterial effects against gram-negative, gram-positive, and acid-fast bacteria. It exhibits high solubility in methanol (MeOH) and serves as a malarial pigment analogue for drug development, as well as a potential antibacterial agent.