mc gly gly phe gly

MC-Gly-Gly-Phe-Gly (DSN28369) is a heterobifunctional linker, and useful to make antibody drug conjuate (ADC).

MC-Gly-Gly-Phe-Gly-PAB-MMAE (Compound SMP-81641) is a linker-drug conjugate. It serves as a control for ADCs and is applicable in tumor research.

MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH is a degradable ADC linker used for synthesizing ADCs (antibody-drug conjugates).

Mc-Gly-Gly-Phe-Gly-PAB-OH is a cleavable linker used for the synthesis of antibody-drug conjugates (ADCs).

MC-Gly-Gly-Phe-Gly-(R)-Cyclopropane-Exatecan is an agent-linker conjugate for antibody-drug conjugates (ADCs), incorporating Exatecan, a DNA Topoisomerase I inhibitor (IC 50 = 2.2 μM) [1].

MC-Gly-Gly-Phe-Gly-(S)-Cyclopropane-Exatecan is a agent-linker conjugates for ADC , consisting Exatecan . Exatecan is a DNA Topoisomerase I inhibitor (IC 50 =2.2 μM) [1] .

Mc-Gly-Gly-Phe-Gly-PAB-OH (Mc-GGFG-PAB-OH) TFA is a cleavable linker used in the synthesis of antibody-drug conjugates (ADCs).

MC-Gly-Gly-Phe-Gly-Cyclobutanecarboxylic-Exatecan is an agent-linker conjugate designed for antibody-drug conjugate (ADC) applications, comprised of an ADC linker (MC-Gly-Gly-Phe-Gly-Cyclobutanecarboxylic acid) and the DNA topoisomerase I inhibitor, Exatecan. This conjugate is utilized in cancer research [1].

MC-Gly-Gly-Phe-Gly-amide-cyclopropanol-amide-Exatecan is an antibody-drug conjugate (ADC)[1].

MC-Gly-Gly-Phe-Gly-NH-CH2-O-cyclopropane-CH2COOH, a derivative of camptothecin, is utilized in the development of antibody drug conjugates (ADC) [1].

MC-Gly-Gly-Phe-Gly-GABA-Exatecan, functioning both as an ADC linker agent and a topoisomerase inhibitor (Exatecan), displays cytotoxic and antitumor properties in vitro and in vivo [1] [2]. It specifically targets various antibodies and boasts an IC 50 of 22 μM.

MC-Gly-Gly-Phe is a cleavable linker used for antibody-drug conjugates (ADC).

MC-Gly-Gly-Phe-Exatecan analog 38 (Compound L-II-4) forms part of an antibody-drug conjugate (drug-linker conjugate for ADC), consisting of an ADC cytotoxic component and an ADC linker. It can be utilized in synthesizing ADCs such as ADC-II-15 and ADC-III-13, and is applicable in cancer research.

MC-Gly-Gly-{D-Phe}-Gly-NH-CH2-O-CH2COOH is a cleavable ADC linker employed in the production of antibody-drug conjugates (ADCs) [1].

MC-Gly-Gly-D-Phe, a cleavable linker, is utilized in the synthesis of antibody-drug conjugates (ADC).

MC-Gly-Gly-Phe-Boc plays a critical role in the synthesis of antibody-drug conjugates (ADCs) targeting Trastuzumab. It is also utilized in cancer research [1].

MC-Gly-Gly-Phe-OSu is an ADC linker used in cancer research.

Compound D5 (Fomc-Gly-Gly-Phe-Gly-OH) serves as a synthetic intermediate in the construction of an ADC dual-drug-linker, and it is a crucial component for the assembly of this ADC dual-drug linking unit [1].

Adrenocorticotropic Hormone (ACTH) (4-10), human is a potent agonist of the melanocortin receptor (MC4R).

Trastuzumab rezetecan (SHR-A1811) is an antibody-drug conjugate (ADC) targeting HER2. It is composed of a humanized anti-HER2 antibody, a cleavable linker MC-Gly-Gly-Phe-Gly, and an effective payload of the topoisomerase I inhibitor Rezetecán. Trastuzumab rezetecan is utilized in the research of HER2-positive breast cancer.

Mc-Lys(PEG12)-Cap-Ala-Ala-PABC serves as a linker for MC-Gly-Gly-Phe-Gly-(R)-Cyclopropane-Exatecan.