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By Target- Cytochromes P450
- HBV(1)
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Results for "
mb 6866
" in TargetMol Product Catalog.- Inhibitors & Agonists1
- PradefovirRemofovir, MB-6866, MB-06866, ICN-2001-3, ICN-20013T28449625095-60-5Pradefovir (Remofovir) is a reverse transcriptase inhibitor potentially for treatment of chronic HBV infection. Pradefovir is also a liver-targeted prodrug of adefovir. After metabolic activation, Pradefovir was converted to PMEA (9-(2-phosphonylmethoxyethyl)adenine) in human liver microsomes with a K(m) of 60 microM, a maximum rate of metabolism of 228 pmol/min/mg protein, and an intrinsic clearance of about 359 ml/min.
- $238
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Other Forms of Products
- Pradefovir mesylate
Remofovir mesylate, Pradefovir mesilate, Hepavir BT19526625095-61-6Pradefovir mesylate (Hepavir B) is converted to 9-(2-phosphonylmethoxyethyl)adenine (PMEA) in human liver microsomes with Km of 60 μM.- $139
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