malonic acid

Malonic acid (propanedioic acid) is the archetypal example of a competitive inhibitor: it acts against succinate dehydrogenase (complex II) in the respiratory electron transport chain. Malonic acid is found to be associated with malonyl-CoA decarboxylase deficiency, which is an inborn error of metabolism.

Nodakenetin-Glucose-malonic acid is a natural compound [1] characterized by its potential biological activities and unique chemical properties.

MALONIC ACID, (P-HYDROXYBENZYL)- (7CI) (2-[(4-hydroxyphenyl)methyl]propanedioic acid) is a natural product.

Dimethylmalonic acid(2,2-Dimethylmalonic acid) is a short-chain dicarboxylic acid found in human serum that can be used to prevent or retard denaturation of fish actinomyosin in freezing buffer solution (pH 7).

Methylmalonic acid is an indicator of vitamin B-12 deficiency in cancer patients.Methylmalonic acid is a competitive succinate dehydrogenase inhibitor.

Ethylmalonic acid is potentially toxic, non-carcinogenic, and has been associated with anorexia nervosa and methoxy decarboxylase deficiency.

2-Hydroxymalonic acid inhibits serine racemase (IC₅₀ = 94 µM) and can be used in related research in the field of life sciences.

Aminomalonic acid is an amino endogenous metabolite that acts as a potent inhibitor of L-asparagine synthetase from Leukemia 5178Y AR and mouse pancreas in vitro (Leukemia 5178Y AR: Ki= 0.0023 M, mouse pancreas: Ki= 0.0015 M). It has the potential to be used as a biomarker to distinguish between different stages of melanoma metastasis.

3-Ethoxy-3-oxopropanoic acid (Monoethyl malonic acid) belongs to the class of organic compounds known as dicarboxylic acids and derivatives. These are organic compounds containing exactly two carboxylic acid groups. 3-Ethoxy-3-oxopropanoic acid exists as a solid, soluble (in water), and a weakly acidic compound (based on its pKa). 3-Ethoxy-3-oxopropanoic acid has been primarily detected in blood. Within the cell, monoethyl malonic acid is primarily located in the cytoplasm.

Mesoxalate sodium (monohydrate) is primarily located in the cytoplasm within the cell. Mesoxalic acid can be biosynthesized from malonic acid. Outside of the human body, mesoxalic acid can be found in cereals and cereal products, common pea, and herbs and spices.

3-Oxooctadecanoic acid (3-Oxostearic acid), a saturated fatty acid (SFA), acts as an intermediate in fatty acid biosynthesis, originating from malonic acid via the enzyme [1].