m 122

M122 is a selective histone deacetylase HDAC1 and HDAC2 inhibitor and potent antitumor agent.

M133 is a selective histone deacetylase HDAC1 and HDAC2 inhibitor and potent antitumor agent.

ZZM-1220, a covalent inhibitor of histone lysine methyltransferase G9a/GLP, exhibits IC50 values of 458 nM for G9a and 924 nM for GLP. It effectively inhibits H3K9me2 in cells, induces apoptosis in triple-negative breast cancer (TNBC) cells, and arrests the cell cycle at the G2/M phase [1].

Hordenine (Standard) is a reference standard for research and analysis in studies involving Hordenine. Hordenine, an effective phenylethylamine alkaloid, has antibacterial activities.

Fluorometholone (Standard) is the standard substance of Fluorometholone, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Fluorometholone (Fluoromethalone) is a corticosteroid, most often used after laser-based refractive surgery. It is marketed under the brand names FML (Allergan) and Flarex (Alcon). Fluorometholone acetate ophthalmic suspension is indicated for use in the treatment of steroid responsive inflammatory conditions of the palpebral and bulbar conjunctiva, cornea, and anterior segment of the eye.

Diallyl Trisulfide (Standard) is a reference standard for research and analysis in studies involving Diallyl Trisulfide. Diallyl Trisulfide is an organic polysulfide compound found in garlic that acts as an H2S donor.

Fluorometholone Acetate (Standard) is the standard substance of Fluorometholone Acetate, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Fluorometholone Acetate (Oxylone acetate) is a synthetic corticosteroid, used in the treatment of steroid responsive inflammatory conditions of the eye.

Indicine N-oxide (Standard) is a reference standard for research and analysis in studies involving Indicine N-oxide. Indicine N-oxide (NSC 132319), a pyrrolizidine alkaloid, serves as an antitumor agent in pediatric cancer and solid tumors research.

Fluoronaphthalene (Standard) is the standard substance of Fluoronaphthalene, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Fluoronaphthalene is incompatible with strong oxidizing agents.

Fluoxetine (Standard) is the standard substance of Fluoxetine, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Fluoxetine (LY-110140) is a highly specific serotonin uptake inhibitor and selective 5-hydroxytryptamine (5-HT) reuptake inhibitor. Fluoxetine has antidepressant activity.

Mollugin (Standard) is a reference standard for research and analysis in studies involving Mollugin. Mollugin (Rubimaillin) may be a JAK2 inhibitor and inhibits LPS-induced inflammatory responses by blocking the activation of the JAK-STAT pathway. Mollugin as a candidate for a chemotherapeutic agent in OSCCs via the upregulation of the HO-1 and Nrf2 pathways and the downregulation of NF- κ B. Mollugin may be a novel therapeutic candidate for bone loss-associated disorders including osteoporosis, rheumatoid arthritis, and periodontitis. Also, it has anticancer efficacy, can modulate the HER2 pathway in HER2-overexpressing Y cells with a potential role in the treatment and prevention of human breast and ovarian Y with HER2 overexpression.

Fluphenazine Dihydrochloride (Standard) is the standard substance of Fluphenazine Dihydrochloride, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Fluphenazine dihydrochloride (Prolixin) is an inhibitor of phenothiazine-class D1DR and D2DR; In studies, Fluphenazine can be used to probe the effects and metabolic process of this commonly used dopamine antagonist.

HM-1228 is an inhibitor specifically designed to protect carbon steel from corrosion in produced water systems in oil fields.

Antifungalagent 122 (compound 201), a potent and broad-spectrum antifungal agent, prevents the phase shift in fungi and the formation of fungal biofilms. This compound effectively inhibits the enzymatic activity of CYP3A4-M and CYP3A4-T, with IC50 values of 2.11 and 4.53 µM, respectively. Notably, Antifungalagent 122 exhibits no cytotoxicity.

Carotenoid mixture is a mixture of carotenoids that contains the antioxidative and anti-inflammatory carotenoid capsanthin and the antioxidative vitamin A precursor β-carotene , as well as additional carotenoids and carotenoid esters.1,2,3,4 1.Kim, J.S., Lee, W.M., Rhee, H.C., et al.Red paprika (Capsicum annuum L.) and its main carotenoids, capsanthin and β-carotene, prevent hydrogen peroxide-induced inhibition of gap-junction intercellular communicationChem. Biol. Interact.254146-155(2016) 2.Narisawa, T., Fukaura, Y., Hasebe, M., et al.Prevention of N-methylnitrosourea-induced colon carcinogenesis in rats by oxygenated carotenoid capsanthin and capsanthin-rich paprika juiceProc. Soc. Exp. Biol. Med.224(2)116-122(2000) 3.Horie, S., Okuda, C., T., Y., et al.Purified canola lutein selectively inhibits specific isoforms of mammalian DNA polymerases and reduces inflammatory responseLipids45(8)713-721(2010) 4.Negishi, H., Ueda, Y., and Azuma, M.Antioxidant fat-soluble vitamins and lipid peroxides in serumJ. Clin. Biochem. Nutr.26227-234(1999)