lysosomal cysteine protease

Esomeprazole is the S-isomer of omeprazole, inhibits the lysosomal cysteine protease legumain to prevent cancer metastasis. Esomeprazole is a proton pump inhibitors (PPI).

AC1115 is a highly effective and selective antiviral compound targeting SARS-CoV-2 Mpro and the host lysosomal cysteine protease cathepsin L (CTSL), exhibiting potent antiviral activity.

KGP94 is an inhibitor of cysteine protease Cathepsin L(CTSL).

AC1115 TFA is a potent, selective antiviral drug and the active form of olgotrelvir. AC1115 TFA targets the Mpro of SARS-CoV-2 as well as the host lysosomal cysteine protease cathepsin L (CTSL), exhibiting high antiviral activity.

Aloxistatin (E64d) is an inhibitor of cysteine protease with blood platelet aggregation inhibiting activity. Aloxistatin is an irreversible, membrane-permeable inhibitor of lysosomal and cytosolic cysteine proteases with the ability to inhibit calpain activity in intact platelets.

Cathepsin B is a cysteine protease located within the subcellular endosomes and lysosomal compartments that mediates apoptosis and can be used in cancer research.

Esomeprazole-D3 is a deuterated compound of Esomeprazole. Esomeprazole (T20626) has a CAS number of 119141-88-7. Esomeprazole (T20626) is the S-isomer of omeprazole, inhibits the lysosomal cysteine protease legumain to prevent cancer metastasis. Esomeprazole (T20626) is a proton pump inhibitors (PPI).

N-CBZ-Phe-Arg-AMC hydrochloride (Z-Phe-Arg-Amc HCl) is a substrate for catS protease. CatS protease is an important member of the cysteine protease family and is a lysosomal protease. It is expressed in many inflammatory processes and autoimmune diseases and can be used to assess the activity of lysosomal proteases.