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(1)
By Target- Discoidin Domain Receptor (DDR)
- FLT(1)
- ROS Kinase(1)
- TAM Receptor(1)
- Tyrosine Kinases(1)
- c-Met/HGFR(1)
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By Target By ResearchField- Cancer(1)
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Results for "
ly-2801653 dihydrochloride
" in TargetMol Product Catalog.- Inhibitors & Agonists1
- Merestinib dihydrochlorideLY2801653 dihydrochloride, LY 2801653 dihydrochlorideT158081206801-37-7Merestinib dihydrochloride (LY2801653 dihydrochloride) is an orally available kinase inhibitor with antitumor activity that inhibits MET, AXL, RON, and MKNK1/2, and inhibits the growth of NTRK fusion-carrying tumors.
- $45
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- Merestinib
LY2801653T34551206799-15-6Merestinib (LY2801653) is an orally available, small molecule inhibitor of the proto-oncogene c-Met (Ki: 2 nM) with potential antineoplastic activity. Merestinib electively binds to c-Met, thereby inhibiting c-Met phosphorylation and disrupting c-Met signal transduction pathways. This may induce cell death in tumor cells overexpressing c-Met protein or expressing the constitutively activated c-Met protein.- $45
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