liposome

5A2-SC8 is an ionizable cationic lipid that is an ideal vehicle for the delivery of small RNAs, interacts with negatively charged cell membranes, and can be used for gene delivery and drug delivery.

DOPE (DOPE) is a neutral helper lipid for cationic liposomes.It is used in combination with cationic phospholipids to increase efficiency during DNA transfection studies as a non-viral method of gene delivery.

Dehydroergosterol (DHE) is a naturally occurring fluorescent sterol analog that is a compound for real-time detection/elaboration of the sterol environment and intracellular sterol transport in organisms. Dehydroergosterol is a cholesterol mimetic that binds to cholesterol-binding proteins and can be used for real-time imaging of living cells. Dehydroergosterol is a cholesterol mimetic that binds to cholesterol-binding proteins and can be used for real-time imaging of living cells.

1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol sodium, catalog number T67435 and CAS number 200880-42-8, is a valuable organic compound for life sciences research.

DSPE-PEG 2000 is a non-toxic and biodegradable amphiphilic copolymer that can be used to form micelles to deliver nanoparticles.

DHAPC (1,2-Didocosahexaenoyl-sn-glycero-3-phosphocholine) can be used as a fluorine-18 radiolabeling agent for PET imaging of prostate cancer.

Vaxfectin is a lipid adjuvant used in the development of protein and peptide vaccines.Vaxfectin promotes vaccine immunogenicity.

DSPE-PEG-Azide (MW 2000) has an amphiphilic structure and can form lipid bilayers/micelles in water. It can be used to prepare nanoparticles or liposomes as targeted drug carriers.

Clodronate liposomes are composed of chlorophosphate salts encapsulated within phospholipid bilayer liposomes, which are selectively ingested by macrophages following systemic administration. Within macrophage lysosomes, phosphatases gradually release the chlorophosphate salts from the liposomal vesicles, leading to their intracellular accumulation. Once a threshold concentration is reached, the accumulation results in irreversible damage to the macrophages and induces apoptosis, making clodronate liposomes a useful research tool for investigating macrophage depletion and immune modulation.

D-Lin-MC3-DMA, an ionizable cationic lipid, serves as a potent siRNA delivery vehicle.

ALC-0315 is an ionizable amino lipid that has been used in combination with other lipids to form lipid nanoparticles. Lipid-Nanoparticles have been used in the research of mRNA COVID-19 vaccine

SM-102 is the only ionizable amino cationic lipid currently clinically approved for RNA therapeutics and can be used to synthesize lipid nanoparticles (LNPs). It shows potential in the development of LNPs for the delivery of mRNA-based vaccines.

DODAP is an ionic cationic lipid with low cytotoxicity and high transfection efficiency that can be used to synthesize liposomes and encapsulate biologically active molecules such as mRNA, siRNA and plasmid DNA.

Phosphatidylcholines,soya (Soybean phosphatidylcholine) is a phosphatidylcholine from soybean used in the preparation of liposomes.

1,2-Distearoyl-sn-glycero-3-phosphorylethanolamine (1,2-DSPE) is a phosphatidylethanolamine (PE or GPEtn). The stearic acid moieties are derived from animal fats, cocoa butter, and sesame oil. Phospholipids are ubiquitous in nature and are key components of the lipid bilayer of cells, as well as being involved in metabolism and signaling.

7-Oxotridecanedioic Acid is a biodegradable cationic lipid intermediate for formulating active-agent-loaded lipid nanoparticles.

Oleyl Mesylate, a derivative of oleyl alcohol, can be incorporated into various formulations.

CLinDMA, a cationic lipid, is known to induce an inflammatory response and serves as a precursor in the synthesis of LNP201, a liposome assembly designed for the systemic delivery of siRNA [1].

DOTAP chloride (1, 2-dioleoyl-3-trimethylammonium-propane chloride) is an efficient cationic lipid, and its target is mainly the negatively charged components on the cell membrane. DOTAP chloride binds to negatively charged nucleic acids (such as DNA and RNA) by electrostatic interaction to form complexes, thereby achieving the delivery of nucleic acids.

DSPE-PEG-Biotin (MW 2000) is a PEG-based PROTAC linker for PROTAC synthesis.

DSPE-PEG-Maleimide (MW 5000) is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

DSPE-PEG-OH (MW 2000) is a PEG-based PROTAC linker for PROTAC synthesis.

DSPE-PEG8-Mal is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation via the ubiquitin-proteasome system within cells.

DSPE-PEG(2000)-COOH, a 1,2-distearoyl-sn-glycero-3-PE (DSPE) derivative modified by PEGylation and carboxylation, is a non-toxic and biodegradable amphiphilic copolymer that can be used to form micelles to deliver nanoparticles.