liposome

5A2-SC8 is an ionizable cationic lipid that is an ideal vehicle for the delivery of small RNAs, interacts with negatively charged cell membranes, and can be used for gene delivery and drug delivery.

1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol sodium, catalog number T67435 and CAS number 200880-42-8, is a valuable organic compound for life sciences research.

DSPE-PEG 2000 is a non-toxic and biodegradable amphiphilic copolymer that can be used to form micelles to deliver nanoparticles.

DHAPC (1,2-Didocosahexaenoyl-sn-glycero-3-phosphocholine) can be used as a fluorine-18 radiolabeling agent for PET imaging of prostate cancer.

Vaxfectin is a lipid adjuvant used in the development of protein and peptide vaccines.Vaxfectin promotes vaccine immunogenicity.

DSPE-PEG-Azide (MW 2000) has an amphiphilic structure and can form lipid bilayers micelles in water. It can be used to prepare nanoparticles or liposomes as targeted drug carriers.

DOPE (DOPE) is a neutral helper lipid for cationic liposomes.It is used in combination with cationic phospholipids to increase efficiency during DNA transfection studies as a non-viral method of gene delivery.

Clodronate liposomes are a mixture of chlorophosphate salts encapsulated within liposomes. These liposomes are ingested by macrophages in the body. Within the lysosomes of the macrophages, phosphatases gradually release the chlorophosphate salts from the lipid vesicles, leading to intracellular accumulation. Once a critical concentration is reached, this accumulation causes irreversible damage to the macrophages, triggering apoptosis.

DODAP is an ionic cationic lipid with low cytotoxicity and high transfection efficiency that can be used to synthesize liposomes and encapsulate biologically active molecules such as mRNA, siRNA and plasmid DNA.

PEG(2000)-C-DMG is a polyethylene glycolated derivative of 1,2-Dimyristoyl-sn-glycerol and can be combined with other lipids to form lipid nanoparticles (LNP) for siRNA delivery.

(Rac)-DSPG sodium ((Rac)-1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol sodium) is a derivative of phosphatidylglycerol, which, as an amphiphilic molecule, is commonly used in the study of drug delivery and biofilm research.

G0-C14 is a cationic lipid-like molecule commonly used for synthesizing nanoparticles and vaccine delivery.

NT1-O14B is a novel class of neurotransmitter tryptophan lipids (NT-lipidoids).NT1-O14B can be combined with small molecule drugs (e.g., AmB) and biomolecules (e.g., Tau-ASO) and gene editing proteins (GFP-Cre) to form new neurotransmitter-derived lipid nanoparticles (NT-LNPs) that have blood-brain-barrier (BBB) permeability. Enhanced lipid hydrophobicity and membrane fusion capabilities are commonly used for delivery of nucleic acids such as mRNA, siRNA and DNA.

C14-4 (C14-494) is an ionizable lipid nanoparticle used for delivering CAR mRNA to primary human T cells.

DPhPC is a synthetic liposome used to synthesize liposomes commonly used in artificial membrane matrices.DPhPC bilayers do not allow ion leakage in the absence of pore ion channels.DPhPC can be used to study channel proteins and membrane structure.

CLinDMA, a cationic lipid, is known to induce an inflammatory response and serves as a precursor in the synthesis of LNP201, a liposome assembly designed for the systemic delivery of siRNA [1].

Dimyristoylphosphatidylcholine (DMPE) is a liposome utilized for the delivery of agents [1].

1-Oleoyl-2-palmitoyl-sn-glycero-3-phosphatidylcholine (PC), derived from oleic acid, is used in liposome synthesis [1].

Dielaidoylphosphatidylethanolamine is a liposome utilized for the delivery of agents [1].

18:1 Ethylene Glycol is a liposome utilized for agent delivery.

Phospholipid-PEG-Biotin (MW 3400) is a derivative of phospholipid PEG featuring biotin and a phospholipid connected via a linear PEG linker. This compound can bind avidinylated antibodies and is used to modify liposome and cell surfaces, as well as pancreatic islets in cell transplantation applications [1] [2] [3].

Phospholipid-PEG-Biotin (MW 20000 and MW 3400) is a derivative combining biotin and phospholipid via a linear PEG linker, capable of interacting with avidinylated antibodies. This compound facilitates the modification of liposome and cell surfaces, including pancreatic islets for cell transplantation [1] [2] [3].

DOPE-mPEG (MW 2000), a polydisperse phospholipid PEG (or DOPE liposome), facilitates the targeted delivery of liposomal drugs and the formation of giant unilamellar vesicles (GUVs). Its presence notably diminishes the liposome's pH-sensitivity in a concentration-dependent manner [1] [2] [3].

DOTMA (N-(1-(2,3-dioleyloxy)propyl)-N,N,N-trimethylammonium) is a tetra-methylated DOTA analogue. DOTMA is a cationic lipid and can be used as a non-viral vector for gene therapy. It has been used as a component in liposomes that can be used to encapsulate siRNA, microRNAs, and oligonucleotides and for gene transfection in vitro. It exhibits effective in vitro and in vivo gene transfection. DOTMA induces a positive charge on the liposomes and thus promotes efficient liposome- cell membrane interaction.