liposome

5A2-SC8 is an ionizable cationic lipid that is an ideal vehicle for the delivery of small RNAs, interacts with negatively charged cell membranes, and can be used for gene delivery and drug delivery.

DOPE (DOPE) is a neutral helper lipid for cationic liposomes.It is used in combination with cationic phospholipids to increase efficiency during DNA transfection studies as a non-viral method of gene delivery.

Dehydroergosterol (DHE) is a naturally occurring fluorescent sterol analog that is a compound for real-time detection/elaboration of the sterol environment and intracellular sterol transport in organisms. Dehydroergosterol is a cholesterol mimetic that binds to cholesterol-binding proteins and can be used for real-time imaging of living cells. Dehydroergosterol is a cholesterol mimetic that binds to cholesterol-binding proteins and can be used for real-time imaging of living cells.

1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol sodium, catalog number T67435 and CAS number 200880-42-8, is a valuable organic compound for life sciences research.

DSPE-PEG 2000 is a non-toxic and biodegradable amphiphilic copolymer that can be used to form micelles to deliver nanoparticles.

DHAPC (1,2-Didocosahexaenoyl-sn-glycero-3-phosphocholine) can be used as a fluorine-18 radiolabeling agent for PET imaging of prostate cancer.

Vaxfectin is a lipid adjuvant used in the development of protein and peptide vaccines.Vaxfectin promotes vaccine immunogenicity.

DSPE-PEG-Azide (MW 2000) has an amphiphilic structure and can form lipid bilayers/micelles in water. It can be used to prepare nanoparticles or liposomes as targeted drug carriers.

Clodronate liposomes are composed of chlorophosphate salts encapsulated within phospholipid bilayer liposomes, which are selectively ingested by macrophages following systemic administration. Within macrophage lysosomes, phosphatases gradually release the chlorophosphate salts from the liposomal vesicles, leading to their intracellular accumulation. Once a threshold concentration is reached, the accumulation results in irreversible damage to the macrophages and induces apoptosis, making clodronate liposomes a useful research tool for investigating macrophage depletion and immune modulation.

DODAP is an ionic cationic lipid with low cytotoxicity and high transfection efficiency that can be used to synthesize liposomes and encapsulate biologically active molecules such as mRNA, siRNA and plasmid DNA.

DSPE-PEG(2000)-COOH, a 1,2-distearoyl-sn-glycero-3-PE (DSPE) derivative modified by PEGylation and carboxylation, is a non-toxic and biodegradable amphiphilic copolymer that can be used to form micelles to deliver nanoparticles.

PEG(2000)-C-DMG is a polyethylene glycolated derivative of 1,2-Dimyristoyl-sn-glycerol and can be combined with other lipids to form lipid nanoparticles (LNP) for siRNA delivery.

Ceramide 1-phosphate, a bioactive lipid, is a critical component of sphingolipids. It plays versatile roles in various cellular behaviors, including differentiation, migration, proliferation, and apoptosis.

1-Palmitoyl-2-hydroxy-sn-glycero-3-PE is a naturally occurring lysophospholipid and endogenous metabolite used in biochemical experiments and drug synthesis research.

BAMEAO16B is a lipid nanoparticle that incorporates disulfide bonds for efficient delivery of Cas9 mRNA and sgRNA into cells. In the intracellular environment, BAMEAO16B responds to reduction by releasing RNA, facilitating genome editing. This compound is valuable for gene editing research purposes.

(Rac)-DSPG sodium ((Rac)-1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol sodium) is a derivative of phosphatidylglycerol, which, as an amphiphilic molecule, is commonly used in the study of drug delivery and biofilm research.

6-Oxohexyl 2-hexyldecanoate is a lipid product utilized for drug delivery [1].

Decanoic acid, 2-hexyl-, 6-oxohexyl ester-1, is a lipid compound utilized in drug delivery systems [1].

TCL053, an ionizable lipid carrier, efficiently facilitates the introduction of active components, particularly nucleic acids, into cells. In combination with Dipalmitoylphosphatidylcholine (DPPC), Polyethylene glycol dimyristoyl glycerol (PEG-DMG), and cholesterol, TCL053 composes a lipid nanoparticle (LNP) system capable of delivering Cas9 mRNA and sgRNA into skeletal muscle [1] [2].

Lipid 29, an ionizable amino lipid, can be utilized to create lipid nanoparticles [1].

G0-C14 is a cationic lipid-like molecule commonly used for synthesizing nanoparticles and vaccine delivery.

DSPE-PEG-SH (MW 2000), a pegylated phospholipid featuring a reactive thiol group for forming covalent thioether linkages with maleimide, is an amphiphilic polymer capable of self-assembling into lipid bilayers in aqueous solutions. It is utilized in encapsulating agents within drug delivery systems, including mRNA vaccines.

NT1-O14B is a novel class of neurotransmitter tryptophan lipids (NT-lipidoids).NT1-O14B can be combined with small molecule drugs (e.g., AmB) and biomolecules (e.g., Tau-ASO) and gene editing proteins (GFP-Cre) to form new neurotransmitter-derived lipid nanoparticles (NT-LNPs) that have blood-brain-barrier (BBB) permeability. Enhanced lipid hydrophobicity and membrane fusion capabilities are commonly used for delivery of nucleic acids such as mRNA, siRNA and DNA.

DSPE-PEG-Maleimide, a compound comprised of DSPE phospholipid and maleimide, is utilized for preparing nanostructured lipid carriers, enhancing both blood circulation time and stability of encapsulated agents [1] [2]. The variant DSPE-PEG5000-Mal includes PEG5000, further contributing to its utility in drug delivery systems.