lhomocysteine

L-Homocysteine is a biological thiol involved in various diseases and pathological conditions. It is a marker for atherosclerosis and can exacerbate intestinal inflammation in inflammatory bowel disease (IBD) by promoting the expression of 5-LOX and COX-2, making it suitable for inducing vascular endothelial inflammation models.

L-Homocysteine thiolactone hydrochloride is neurotoxic and can induce epilepsy and Alzheimer's disease.

S-N6-Methyladenosylhomocysteine (Chart 1-1) is a potent inhibitor of the histone methyltransferase DOT1L, with an IC50 of 0.29 μM. This compound plays a significant role in cancer research.

(S)-Tubercidinylhomocysteine (Page 46) is a potent inhibitor of S-adenosylmethionine-dependent methyltransferases. It is useful in studies of herpes viruses (HSV) and vaccinia virus (VV).

S-Aristeromycinylhomocysteine is an inhibitor of adenosylmethionine decarboxylase.

Palmitoyl homocysteine is a lipid nanocarrier.

S-Hydroxyethylhomocysteine is a bioactive chemical.

3-Deazaadenosine hydrochloride is an inhibitor of S-adenosylhomocysteine hydrolase (Ki: 3.9 µM). It has anti-inflammatory, anti-proliferative, and anti-HIV activity.

3-Deazaneplanocin A HCl is a synthetically derived inhibitor of the histone methyltransferase (EZH2) and S-adenosylhomocysteine hydrolase (SAHH). By regulating epigenetic methylation pathways, 3-deazaneplanocin A induces apoptosis and inhibits tumor cell proliferation, demonstrating significant antitumor activity in various tumor models. 3-deazaneplanocin A HCl can be used in research on epigenetic regulation, tumorigenesis and progression, and stem cell differentiation.

Adenosine Dialdehyde (Periodate-oxidized adenosine) is a purine nucleoside analogue. Adenosine Dialdehyde is a potent inhibitor of S-Adenosylhomocysteine hydrolase (SAHH) (Ki=3.3 nM). Adenosine Dialdehyde exhibits potent anti-tumor activity in vivo.

DL-Homocysteine thiolactone hydrochloride (DL-Homocysteinethiolactone hydrochloride) is a cysteine derivative that binds to and induces conformational changes in various plasma proteins, slowing coagulation and inducing oxidative stress. It decreases left ventricular systolic blood pressure and cardiac force and induces seizures in vivo.

3-Deazaadenosine (3-DAA) is a potent S-adenosylhomocysteine (SAH) hydrolase inhibitor. It inhibits methylation reactions by inducing intracellular SAH accumulation, exhibiting antiviral, anti-inflammatory, and immunomodulatory activities.

Aristeromycin (U 99468) is a broad-spectrum antiviral antibiotic that targets RNA viruses and is an inhibitor of S-adenosylhomocysteine hydrolase (AHCY).

L-Homocysteine-D is the deuterium-labeled variant of L-Homocysteine (T19392).

SAHO is a catechol‑O‑methyltransferase (COMT) inhibitor with an IC50 value of 860 μM, and can be used in research related to methylation reaction regulators.

N-butyryl-L-Homocysteine thio-lactone, an analog of N-butyryl-L-homoserine lactone, is a small diffusible signaling molecule involved in quorum sensing for controlling gene expression and cellular metabolism. It induces violacein expression in C. violaceum mutants usually not able to produce acylhomoserine lactone (AHL), regulating genes like LuxIR family transcriptional regulators.

DL-Homocysteine (2-Amino-4-mercaptobutyric acid) is a potential marker for tumor cell growth. increased plasma homocysteine is a risk factor for coronary heart disease and carcinogenesis.

SARS-CoV-2-IN-76 (compound 1) operates as an inhibitor of both nsp14-viral cap N7 methyltransferase and PLpro in severe acute respiratory syndrome coronavirus (SARS-CoV-2) [1].

DL-Homocysteine-3,3,4,4-D4 is a deuterated compound of DL-Homocysteine (T4863) (2-Amino-4-mercaptobutyric acid).DL-Homocysteine is a weak neurotoxin that affects canine uric acid production.

DL-Homocysteine (Standard) is a reference standard for research and analysis in studies involving DL-Homocysteine. DL-Homocysteine (2-Amino-4-mercaptobutyric acid) is a potential marker for tumor cell growth. increased plasma homocysteine is a risk factor for coronary heart disease and carcinogenesis.

S-(5‘-Adenosyl)-L-Homocysteine-[D4] (Standard) is a reference standard of S-(5‘-Adenosyl)-L-Homocysteine-[D4] intended for quantitative analysis, quality control, and related biochemical research applications.

Dl-Homocysteine-3,3,4,4-D4 (Standard) is a reference standard of Dl-Homocysteine-3,3,4,4-D4 intended for quantitative analysis, quality control, and related biochemical research applications. DL-Homocysteine-3,3,4,4-d4 is a deuterated compound of DL-Homocysteine (2-Amino-4-mercaptobutyric acid).DL-Homocysteine is a weak neurotoxin that affects canine uric acid production.

S-Inosyl-L-homocysteine is a nucleoside metabolite.

SAH (SAH (S-Adenosylhomocysteine)) is an inhibitor for the METTL3-METTL14 heterodimer complex (METTL3-14, IC50: 0.9 μM).