Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty
Filter
Applied FilterClear all
TargetMol | Tags By Target
  • Ras
    (3)
  • Others
    (1)
Filter
Search Result
Results for "

kras g12c inhibitor 14

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    4
    TargetMol | Inhibitors_Agonists
KRAS G12C inhibitor 14
T117682349393-95-7
KRAS G12C inhibitor 14 is a potent compound with an IC50 of 18 nM [1].
  • Inquiry Price
8-10 weeks
Size
QTY
KRASG12C IN-14
T200204
KRASG12C IN-14 (compound 15), a potent inhibitor specifically designed for the KRAS G12C mutation, exhibits impressive efficacy in impeding CYPA-dependent KRAS-BRAF interaction and ERK phosphorylation in NCI-H358 cells, both with an IC 50 of 0.002 μM.
  • Inquiry Price
Size
QTY
KRAS inhibitor-37
T2012593058573-95-5
KRAS inhibitor-37 (compound 2) is a potent inhibitor of KRAS, exhibiting low dissociation constants (KD) with various KRAS mutations: wild type (0.004 nM), G12D (0.041 nM), G12C (0.019 nM), and G12V (0.144 nM). This compound effectively inhibits cell proliferation, demonstrating half-maximal inhibitory concentrations (IC50) ranging from <2 nM to 14 nM in H358, SW620, and PANC08.13 cell lines. KRAS inhibitor-37 holds potential for cancer research applications.
  • Inquiry Price
3-6 months
Size
QTY
kras inhibitor-14
T632352230873-78-4
KRAS inhibitor-14 is a potent inhibitor of KRAS G12C (IC50: 0.249 μM). KRAS inhibitor-14 exhibited p-ERK inhibition in MIA PaCA-2, A549 cells with IC50s of 1.12, >33.3 μM, respectively. KRAS inhibitor-14 has potential to be investigated in pancreatic, colorectal and lung cancers.
  • Inquiry Price
8-10 weeks
Size
QTY