kat6a

CTX-0124143 is a histone acetyltransferase inhibitor with an IC50 value of 1.0 μM for KAT6A.CTX-0124143 can be used to study cellular senescence.

KAT6A-IN-2 (compound 7) is an inhibitor of KAT6A.

KAT6A-IN-1 (compound 5) is an inhibitor of KAT6A.

KAT6-IN-3 (compound 10) competitively targets and binds to KAT6A and KAT6B.

BAY-184 is a selective oral inhibitor of KAT6A and KAT6B, with IC50 values of 71 nM and 83 nM, respectively. It suppresses ERα transcriptional activity and hinders cell proliferation across various breast cancer subtypes, as well as tumor growth.

WM-1119 is a highly potent, selective KAT6A B inhibitor

MOZ-IN-3 (Compound 6j), a potent KAT6A (MOZ) acetyltransferase inhibitor with an IC50 of 30 nM, exhibits antitumor activity against multiple myeloid leukemia cell lines, including HL-60, U937, SKNO-1, and K562. This compound also demonstrates favorable metabolic stability and pharmacokinetics [1].

MW-2474 is an inhibitor of the lysine acetyltransferase KAT6A.

PF-9363 (CTX-3648) is a potent and high selective KAT6A KAT6B inhibitor. PF-9363 can be used for the research of cancer.