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Search Results for " insulin-induced "

Targets

46

Compounds

12

Natural Products

39

Recombinant Proteins

1

Libraries

Cat No. Product Name Synonyms Targets
T9266 Fatostatin Lipid , Fatty Acid Synthase
Fatostatin is a specific inhibitor of SREBP activation, it impairs the activation of SREBP-1 and SREBP-2. Fatostatin binds to SCAP (SREBP cleavage-activating protein), and inhibits the ER-Golgi translocation of SREBPs.
T6832 Fatostatin hydrobromide Fatostatin HBr,Fatostatin A,Fatostatin A HBr,Fatostatin NPC1L1 , Fatty Acid Synthase
Fatostatin hydrobromide (Fatostatin A HBr) ia an inhibitor of sterol regulatory element binding protein (SREBP). It impairs the activation of SREBP-1 and SREBP-2.
TP1376 GLP-1(7-37) acetate(106612-94-6 free base) GLP-1(7-37) acetate Others , Glucagon Receptor
Glp-1(7-37) acetate is an intestinal insulin hormone that enhances glucose-induced insulin secretion.
T8773 MID-1 Others , IGF-1R
MID-1 is an inhibitor of MG53-IRS-1 (Mitsugumin 53-Insulin Receptor Substrate-1) interaction. It disrupts molecular association of MG53 with IRS-1 and abolishes MG53-induced IRS-1 ubiquitination and degradation in skelet...
T13867 RH01386 Others
RH01386 is a small molecule that can prevent ER stress-induced β cell dysfunction and death, and inhibits proapoptotic gene expression,has the potential for type 2 diabetes treatment. RH01386 restores ER stress-impaired ...
TP2209L Xenin 8 acetate Xenin 8 acetate (117442-28-1 Free base) IGF-1R
Xenin 8 acetate is a biologically active fragment of Xenin in the neurotensin/xenopsin family. Xenin 8 acetate augments Arginine-induced insulin release (by 40%) and potentiates the glucagon responses to both Arginine (b...
T15368L Galantide acetate Galantide acetate(138579-66-5 Free base) Neuropeptide Y Receptor
Galantide acetate, a non-specific galanin receptor antagonist, is a peptide consisting of fragments of galanin and substance P. Galantide acetate recognizes two classes of galanin binding sites (KD<0.1 nM and ~6 nM) in t...
T2160 Suramin Sodium Salt BAY-205,Suramin hexasodium salt,NF-060 Apoptosis , Phosphatase , SARS-CoV , Sirtuin , Reverse Transcriptase , Topoisomerase , Parasite
Suramin Sodium Salt (BAY-205) is a sodium salt form of suramin, a polysulphonated naphthylurea with potential antineoplastic activity. Suramin blocks the binding of various growth factors, including insulin-like growth f...
TP1141 GLP-1(7-36), amide acetate GLP-1(7-36) Acetate,Human GLP-1-(7-36)-amide Acetate
GLP-1(7-36) Acetate is a major intestinal hormone that stimulates glucose-induced insulin secretion from β cells.
T26617 AMG-221 AMG221
AMG-221 is a potent and selective 11β-HSD1 inhibitor. AMG-221 decreased fed blood glucose and insulin levels and reduced body weight in diet-induced obesity mice.
T37892 GLP-1(7-36), amide TFA
GLP-1(7-36), amide TFA is a prominent intestinal hormone known to stimulate glucose-induced insulin secretion from β cells[1].
T34600 Secretin (1-6) Secretin,N-terminal hexapeptide
Secretin (1-6) is the N-terminal part of secretin. It can produce vitro glucose-dependent insulin release induced by secretin.
T27324 FK614 FK 614,ATx-08-001,ATx-08001,FK-614
FK-614 is a selective agonist of peroxisome proliferator-activated receptor gamma. FK-614 improves peripheral glucose utilization while decreases hepatic insulin extraction in alloxan-induced diabetic dogs.
T30261 AZD6482 (S-isomer) AZD-6482,AZD 6482,AZD6482 (S),AZD6482
AZD6482 (S-isomer) is a potent, selective, ATP-competitive PI3Kβ inhibitor (IC(50) 0.01 μm), which can inhibit insulin-induced in vitro glucose uptake by human adipocytes (IC(50) is 4.4 μm).
TP2033 [Des-His1,Glu9]-Glucagon amide des-His1-[Glu9]-Glucagon (1-29) amide
Glucagon receptor antagonist (pA2 = 7.2 for inhibition of glucagon-induced adenylyl cyclase activation in rat liver membranes); displays no agonist activity. Enhances glucose-stimulated pancreatic insulin release in vitr...
T37120 1,2,3-Triundecanoyl Glycerol
1,2,3-Triundecanoyl glycerol is a triacylglycerol that contains undecanoic acid at thesn-1,sn-2, andsn-3 positions. Dietary administration of a 7:3 (w/w) mixture of 1,2,3-triundecanoyl glycerol and corn oil prevents fast...
T3984 GLP-1(7-36), amide MKC 253,Human GLP-1-(7-36)-amide,Glucagon-like Peptide 1 (7-36) amide,Glucagon-Like Peptide (GLP) I (7-36), amide, human,GLP-1(7-36),GLP-1-(7-36)-amide Glucagon Receptor
GLP-1(7-36), amide (MKC 253) is a peptide hormone released from intestinal L-cells upon nutrient consumption. It binds the GLP-1 receptor in the pancreas and displays various antidiabetic effects by potentiating glucose-...
T71981 Gliclazide-d4
Gliclazide-d4 is intended for use as an internal standard for the quantification of gliclazide by GC- or LC-MS. Gliclazide is a sulfonylurea and an inhibitor of pancreatic β-cell ATP-sensitive potassium (KATP) channels. ...
T26724 AZD-9164 bromide AZD9164,AZD-9164,AZD 9164
AMG-221 is a potent and selective 11β-HSD1 inhibitor. AMG 221 potently blocked 11β-HSD1 activity, producing sustained inhibition for the 24-hour study duration as measured in ex vivo adipose samples. AMG-221 decreased fe...
T40518L C-Peptide 2, rat acetate C-Peptide 2, rat acetate (41594-08-5 Free base) Others
C-Peptide 2, rat acetate is a proinsulin component of inhibiting glucose-induced insulin secretion, consisting of acetate and a polypeptide composed of 31 amino acid residues [1] [2].
T15043 D5D-IN-326 Others
D5D-IN-326 is an orally active delta-5 desaturase (D5D) inhibitor (IC50s: 72 and 22 nM for rat and human D5D in enzymic and cell-based assays). It has no effect on D6D or D9D activity. D5D-IN-326 reduces insulin resistan...
T82295 GluR23Y
GluR23Y, a biologically active peptide, was utilized in an ELISA-based cell-surface assay to assess insulin-stimulated endocytosis of native AMPA receptors in cultured hippocampal neurons. GluR23Y effectively inhibited t...
T83694 Gastric Inhibitory Peptide (1-42) (porcine) TFA GIP (1-42),Glucose-dependent Insulinotropic Polypeptide (1-42)
Gastric inhibitory peptide (GIP) (1-42), an endogenous incretin hormone comprising 42 amino acids, promotes insulin secretion. Expressed in the intestinal neuroendocrine K cells and submandibular gland, it enters circula...
T35622 FKGK 18
FKGK 18 is an inhibitor of group VIA (GVIA) calcium-independent phospholipase A2 (iPLA2). It inhibits GVIA iPLA2 by 99.9% at 0.091 mole fraction in a mixed micelle activity assay and is selective for GVIA iPLA2 over GIVA...
TP1954 PHM-27 (human)
Endogenous peptide product of human prepro-VIP and analog of porcine PHI-27; potent agonist for the human calcitonin receptor (EC50 = 11 nM). Transgenic mice expressing the human VIP/PHM 27 gene in pancreatic β-islets di...
T71559 Melanotan II acetate
Melanotan II acetate is an agonist of melanocortin receptor 1 (MC1R), MC3R, MC4R, and MC5R. It has been shown to improve recovery of sciatic nerve function after mechanical injury and increase cisplatin-induced decreases...
T21681 AACOCF3 Arachidonyl trifluoromethyl ketone,Arachidonyltrifluoromethane Phospholipase
AACOCF3 is a cell-permeable trifluoromethyl ketone analog of arachidonic acid. It is a potent and selective slow binding inhibitor of the 85-kDa cytosolic phospholipase A2 (cPLA2). By blocking the production of arachidon...
T68976 Piragliatin
Piragliatin, also known as RO4389620, is a glucokinase activator. Piragliatin greatly enhances glucose-induced pancreatic islet respiration and insulin release. Piragliatin lowers plasma glucose both in the postabsorptiv...
T72591 Sp-5,6-DCl-cBIMPS
Sp-5,6-DCl-cBIMPS is a potent and specific cAMP-dependent protein kinases (cAMP-PK) activator. Sp-5,6-DCl-cBIMPS stimulates insulin release. Sp-5,6-DCl-cBIMPS inhibits U46619-induced activation of Rho, Gq and G12/G13 in ...
T35809 C20 Sphingomyelin (d18:1/20:0)
C20 Sphingomyelin is a naturally occurring sphingolipid. Levels of C20 sphingomyelin are upregulated in the hippocampus of rats with diabetes induced by streptozotocin and in human plasma where it is positively correlate...
T72460 Dimethyl L-glutamate Dimethyl glutamate
Dimethyl L-glutamate (Dimethyl glutamate), a membrane-permeable analog of Glutamate, can stimulate insulin release induced by Glucose. Dimethyl L-glutamate suppresses the K ATP channel activities. Dimethyl L-glutamate in...
T35799 MBX-8025 (sodium salt)
MBX-8025 is an agonist of peroxisome proliferator-activated receptor δ (PPARδ).1 It is greater than 750- and 2,500-fold selective for PPARδ over PPARα and PPARγ. MBX-8025 (10 mg/kg per day for eight weeks) reduces increa...
T68808 11-Dehydrocorticosterone
11-Dehydrocorticosterone is an endogenous mineralocorticoid. It increases Na+/K+-ATPase mRNA expression in vascular smooth muscle cells and inhibits aldosterone action in B. marinus toad bladder tissue in a concentration...
T36582 Glucocerebrosides (Gaucher's spleen)
Glucocerebrosides are formed by the tethering of glucose to a ceramide by glucosylceramide synthase. They are present in neuronal and non-neuronal mammalian tissues and are found at low quantities in a large number of pl...
T36586 12-PAHSA
Branched fatty acid esters of hydroxy fatty acids (FAHFAs) are newly identified endogenous lipids regulated by fasting and high-fat feeding and associated with insulin sensitivity. Structurally, these esters are comprise...
T70468 MK-8666
MK-8666 is a partial GPCR agonist that is coordinated with the action of GPR40. MK-8666 has been investigated for treatment of type 2 diabetes mellitus.
T69953 MK-8666 Tris
MK-8666 Tris is a partial GPCR agonist that is coordinated with the action of GPR40. MK-8666 has been investigated for treatment of type 2 diabetes mellitus.
T36059 Dichlorphenamide-13C6 Dichlorphenamide-13C6
Dichlorphenamide-13C6is intended for use as an internal standard for the quantification of dichlorphenamide by GC- or LC-MS. Dichlorphenamide is a sulfonamide and an orally bioavailable carbonic anhydrase (CA) inhibitor ...
T82254 GSK-LSD1 Histone Demethylase
GSK-LSD1, an LSD1 inhibitor, decreases food consumption and body weight while enhancing insulin sensitivity and glycemic regulation in murine obesity models. Additionally, it mitigates non-alcoholic fatty liver disease (...
T83827 Adenosine-5'-O-(3-thiotriphosphate) sodium ATPγS,Adenosine 5'-(γ-thio)-triphosphate
Adenosine-5'-O-(3-thiotriphosphate) (ATPγS), an agonist of the purinergic P2Y11 receptor, prompts inositol phosphate accumulation in CHO-K1 cells harboring the human or canine P2Y11 receptor with EC50 values of 1.2 and 1...
T72034 LI-2242 Others
LI-2242 is a potent inositol hexakisphosphate kinase (IP6K) inhibitor with IC50s of 31 nM, 42 nM, 8.7 nM, and 1944 nM for IP6K1, IP6K2, IP6K3, and IPMK, respectively.LI-2242 ameliorated hepatic steatosis by reducing the ...
T35787 Obestatin (human) (trifluoroacetate salt)
Obestatin is a 23 amino acid peptide hormone with a conserved C-terminal glycine residue and amidation site that is formed by cleavage of the ghrelin and obestatin prepropeptide.1It binds to the orphan receptor GPR39 (Kd...
T36427 PACAP (6-27) (human, chicken, mouse, ovine, porcine, rat) (trifluoroacetate salt) PACAP
Pituitary adenylate cyclase-activating peptide (PACAP) (6-27) is a PACAP receptor antagonist with IC50 values of 1,500, 600, and 300 nM, respectively, for rat PAC1, rat VPAC1, and human VPAC2 recombinant receptors expres...
T83802 TNP-ATP sodium
TNP-ATP, a derivative of ATP, acts as an antagonist to the purinergic P2Y1, P2X3, and P2X2/3 receptors, demonstrating selectivity by showing lower inhibitory concentrations (IC50 = 6, 0.9, 7 nM, respectively) compared to...
T83825 Trofinetide acetate NNZ-2566
Trofinetide, derived from the neuroprotective tripeptide Gly-Pro-Glu (an N-terminal sequence of insulin-like growth factor-1, IGF-1), shows promise in various neuroprotective models. At a concentration of 10 nM, it mitig...
T35874 CC260
CC260 is a selective PI5P4Kα and PI5P4Kβ inhibitor with Kis of 40 nM and 30 nM, respectively. CC260 does not inhibit or weakly inhibits other protein kinases, such as Plk1 and RSK2. CC260 can be used for cell energy meta...

Compounds

Fatostatin
T9266
Synonym:
Target: Lipid, Fatty Acid Synthase
Fatostatin hydrobromide
T6832
Synonym: Fatostatin HBr,Fatostatin A,Fatostatin A HBr,Fatostatin
Target: NPC1L1, Fatty Acid Synthase
GLP-1(7-37) acetate(106612-94-6 free base)
TP1376
Synonym: GLP-1(7-37) acetate
Target: Others, Glucagon Receptor
MID-1
T8773
Synonym:
Target: Others, IGF-1R
RH01386
T13867
Synonym:
Target: Others
Xenin 8 acetate
TP2209L
Synonym: Xenin 8 acetate (117442-28-1 Free base)
Target: IGF-1R
Galantide acetate
T15368L
Synonym: Galantide acetate(138579-66-5 Free base)
Target: Neuropeptide Y Receptor
Suramin Sodium Salt
T2160
Synonym: BAY-205,Suramin hexasodium salt,NF-060
Target: Apoptosis, Phosphatase, SARS-CoV, Sirtuin, Reverse Transcriptase, Topoisomerase, Parasite
GLP-1(7-36), amide acetate
TP1141
Synonym: GLP-1(7-36) Acetate,Human GLP-1-(7-36)-amide Acetate
Target:
AMG-221
T26617
Synonym: AMG221
Target:
GLP-1(7-36), amide TFA
T37892
Synonym:
Target:
Secretin (1-6)
T34600
Synonym: Secretin,N-terminal hexapeptide
Target:
FK614
T27324
Synonym: FK 614,ATx-08-001,ATx-08001,FK-614
Target:
AZD6482 (S-isomer)
T30261
Synonym: AZD-6482,AZD 6482,AZD6482 (S),AZD6482
Target:
[Des-His1,Glu9]-Glucagon amide
TP2033
Synonym: des-His1-[Glu9]-Glucagon (1-29) amide
Target:
1,2,3-Triundecanoyl Glycerol
T37120
Synonym:
Target:
GLP-1(7-36), amide
T3984
Synonym: MKC 253,Human GLP-1-(7-36)-amide,Glucagon-like Peptide 1 (7-36) amide,Glucagon-Like Peptide (GLP) I (7-36), amide, human,GLP-1(7-36),GLP-1-(7-36)-amide
Target: Glucagon Receptor
Gliclazide-d4
T71981
Synonym:
Target:
AZD-9164 bromide
T26724
Synonym: AZD9164,AZD-9164,AZD 9164
Target:
C-Peptide 2, rat acetate
T40518L
Synonym: C-Peptide 2, rat acetate (41594-08-5 Free base)
Target: Others
D5D-IN-326
T15043
Synonym:
Target: Others
GluR23Y
T82295
Synonym:
Target:
Gastric Inhibitory Peptide (1-42) (porcine) TFA
T83694
Synonym: GIP (1-42),Glucose-dependent Insulinotropic Polypeptide (1-42)
Target:
FKGK 18
T35622
Synonym:
Target:
PHM-27 (human)
TP1954
Synonym:
Target:
Melanotan II acetate
T71559
Synonym:
Target:
AACOCF3
T21681
Synonym: Arachidonyl trifluoromethyl ketone,Arachidonyltrifluoromethane
Target: Phospholipase
Piragliatin
T68976
Synonym:
Target:
Sp-5,6-DCl-cBIMPS
T72591
Synonym:
Target:
C20 Sphingomyelin (d18:1/20:0)
T35809
Synonym:
Target:
Dimethyl L-glutamate
T72460
Synonym: Dimethyl glutamate
Target:
MBX-8025 (sodium salt)
T35799
Synonym:
Target:
11-Dehydrocorticosterone
T68808
Synonym:
Target:
Glucocerebrosides (Gaucher's spleen)
T36582
Synonym:
Target:
12-PAHSA
T36586
Synonym:
Target:
MK-8666
T70468
Synonym:
Target:
MK-8666 Tris
T69953
Synonym:
Target:
Dichlorphenamide-13C6
T36059
Synonym: Dichlorphenamide-13C6
Target:
GSK-LSD1
T82254
Synonym:
Target: Histone Demethylase
Adenosine-5'-O-(3-thiotriphosphate) sodium
T83827
Synonym: ATPγS,Adenosine 5'-(γ-thio)-triphosphate
Target:
LI-2242
T72034
Synonym:
Target: Others
Obestatin (human) (trifluoroacetate salt)
T35787
Synonym:
Target:
PACAP (6-27) (human, chicken, mouse, ovine, porcine, rat) (trifluoroacetate salt)
T36427
Synonym:
Target: PACAP
TNP-ATP sodium
T83802
Synonym:
Target:
Trofinetide acetate
T83825
Synonym: NNZ-2566
Target:
CC260
T35874
Synonym:
Target:
Cat No. Product Name Synonyms Targets
T4785 Oxfenicine 4-Hydroxy-L-phenylglycine Others
Oxfenicine (4-Hydroxy-L-phenylglycine) is a carnitine palmitoyltransferase-1 inhibitor. Oxfenicine improves whole-body glucose tolerance and insulin sensitivity in high-fat diet-induced obese mouse with insulin resistanc...
T3123 Allicin ERK , IL Receptor , Others , IκB/IKK , p38 MAPK , TNF , ROS , Caspase , Antifection
Allicin exerts antioxidant, bactericidal, anti-cancer, anti-inflammatory activities, it exerts an inhibitory immunomodulatory effect on intestinal epithelial cells. Allicin could significantly inhibit vascular smooth mus...
TN2215 Taurochenodeoxycholic acid sodium Sodium taurochenodeoxycholate Apoptosis , Endogenous Metabolite
Taurochenodeoxycholic acid sodium (Sodium taurochenodeoxycholate) is one of the main bioactive substances of animals' bile acid. Taurochenodeoxycholic acid sodium induces apoptosis and shows obvious anti-inflammatory and...
TN3511 Bi-linderone Others
Bi-linderone shows significant activity against glucosamine-induced insulin resistance in HepG2 cells at a concentration of 1 microg/mL.
TMA0127 Ficusin A transporter , PPAR
Ficusin has antioxidant, antilipidemic and antidiabetic effects, it can lower the levels of fasting blood glucose, plasma insulin, body weight gain in HFD-STZ induced diabetic rats, and can significantly enhance the PPAR...
TL0014 Pinusolide ERK , p38 MAPK , Calcium Channel , Lipoxygenase , PAFR , Caspase , JNK , AMPK
Pinusolide is a platelet activating factor ( PAF) antagonist, it may prove of therapeutic value in the treatment of hypotension, it has antileukemic potential, and could be used to treat neurodegenerative diseases. Pinus...
T81013 Tert-OMe-byakangelicin
Tert-OMe-byakangelicin is a coumarin known to potentiate adrenaline-induced lipolysis and impede insulin-mediated triglyceride synthesis from glucose in adipocytes [1].
TN4997 Serpentine IGF-1R
Serpentine is an alkaloid found in the roots of Rosa Centifolia that acts as an insulin sensitizer to assist insulin in lowering blood glucose.Serpentine activates the phosphorylation of AMPK, which stimulates glucose up...
TN4094 Gallocatechin gallate IL Receptor , NF-κB , ROS , MAPK , PPAR , Fatty Acid Synthase
Gallocatechin gallate has strong antioxidative, and anti-obesity activities, it inhibits 3T3-L1 differentiation and lipopolysaccharide induced inflammation through MAPK and NF-κB signaling; it also may have anti-diabeti...
T80007 Stevisalioside A Phosphatase
Stevisalioside A (Compound 2), isolated from the roots of Stevia serrata, is an orally active antidiabetic agent that inhibits Protein Tyrosine Phosphatase 1B (PTP1B) with an IC50 value of 526.8 μM. It effectively lowers...
TN3364 Agrimonolide Apoptosis , Dehydrogenase , p38 MAPK , ROS , JAK
Agrimonolide, a compound derived from isocoumarins and found mainly in the herb Agrimonia pilosa Ledeb, has significant biological activity. agrimonolide exerts anti-inflammatory effects by inhibiting lipopolysaccharide ...
T83915 Norbixin hydrate
Norbixin, a carotenoid found in B. orellana, exhibits various biological activities including binding to the peroxisome proliferator-activated receptor γ (PPARγ) with a Ki of 1.15 µM in a cell-free assay. At a dosage of ...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-04699 GAD65 Protein, Human, Recombinant (GST) Human Baculovirus-Insect Cells
Glutamate decarboxylase 2, also known as glutamate decarboxylase 65 kDa isoform, 65 kDa glutamic acid decarboxylase, GAD2 and GAD65, is a member of thegroup II decarboxylase family. GAD2 is identified as a major autoanti...
TMPY-03523 ANGPTL4 Protein, Human, Recombinant (His) Human HEK293
ANGPTL4, also known as ANGPTL2, is a protein with hypoxia-induced expression in endothelial cells. It contains 1 fibrinogen C-terminal domain and is expressed at high levels in the placenta, heart, liver, muscle, pancrea...
TMPY-02632 SIRP alpha Protein, Mouse, Recombinant (His) Mouse HEK293
Tyrosine-protein phosphatase non-receptor type substrate 1, also known as SHP substrate 1, Inhibitory receptor SHPS-1, Brain Ig-like molecule with tyrosine-based activation motifs, Macrophage fusion receptor, CD172 antig...
TMPY-06052 SIRP alpha V2 Protein, Human, Recombinant (His) Human HEK293
Tyrosine-protein phosphatase non-receptor type substrate 1, also known as SHP substrate 1, Inhibitory receptor SHPS-1, Brain Ig-like molecule with tyrosine-based activation motifs, Macrophage fusion receptor, CD172 antig...
TMPY-01573 SIRP alpha Protein, Human, Recombinant (G75A, His) Human HEK293
Tyrosine-protein phosphatase non-receptor type substrate 1, also known as SHP substrate 1, Inhibitory receptor SHPS-1, Brain Ig-like molecule with tyrosine-based activation motifs, Macrophage fusion receptor, CD172 antig...
TMPY-06051 SIRP alpha Protein, Human, Recombinant (hFc) Human HEK293
Tyrosine-protein phosphatase non-receptor type substrate 1, also known as SHP substrate 1, Inhibitory receptor SHPS-1, Brain Ig-like molecule with tyrosine-based activation motifs, Macrophage fusion receptor, CD172 antig...
TMPY-05841 SIRP alpha Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
Tyrosine-protein phosphatase non-receptor type substrate 1, also known as SHP substrate 1, Inhibitory receptor SHPS-1, Brain Ig-like molecule with tyrosine-based activation motifs, Macrophage fusion receptor, CD172 antig...
TMPY-06479 Cathepsin H Protein, Human, Recombinant (His) Human HEK293
Proinflammatory cytokines decreased the expression of CTSH in human islets and primary rat beta-cells, and overexpression of CTSH protected insulin-secreting cells against cytokine-induced apoptosis.
TMPY-04081 Cathepsin H Protein, Mouse, Recombinant (His) Mouse HEK293
Proinflammatory cytokines decreased the expression of CTSH in human islets and primary rat beta-cells, and overexpression of CTSH protected insulin-secreting cells against cytokine-induced apoptosis.
TMPY-04878 IGF1/IGF-I Protein, Mouse, Recombinant Mouse Yeast
IGF I, also known as Mechano Growth Factor, somatomedin-C, IGF-I, and IGF1, is a secreted protein that belongs to the insulin family. The insulin family, comprised of insulin, relaxin, insulin-like growth factors I and I...
TMPY-04942 IGF1 LR3 Protein, Human, Recombinant Human Yeast
IGF I, also known as Mechano Growth Factor, somatomedin-C, IGF-I, and IGF1, is a secreted protein that belongs to the insulin family. The insulin family, comprised of insulin, relaxin, insulin-like growth factors I and I...
TMPY-06982 IGF1/IGF-I Protein, Human, Recombinant Human E. coli
IGF I, also known as Mechano Growth Factor, somatomedin-C, IGF-I, and IGF1, is a secreted protein that belongs to the insulin family. The insulin family, comprised of insulin, relaxin, insulin-like growth factors I and I...
TMPJ-00715 FGF-19 Protein, Human, Recombinant (His) Human E. coli
Fibroblast growth factor 19 (FGF19) is a secreted protein which belongs to the FGFs family. FGF19 is expressed in fetal brain, cartilage, retina, and adult gall bladder. FGFs modulate cellular activity via at least 5 dis...
TMPJ-00190 CD38 Protein, Mouse, Recombinant (hFc) Mouse Human Cells
CD38, also called ADP-ribosyl cyclase, is a Type II integral membrane protein with 301 amino acids in length that belongs to the ADP-ribosyl cyclase family.It synthesizes the second messagers cyclic ADP-ribose and nicoti...
TMPY-04394 Glucokinase Protein, Human, Recombinant Human E. coli
Glucokinase belongs to the bacterial glucokinase family. Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. Alternative splicing of this gene results in ...
TMPY-02194 SOCS3 Protein, Human, Recombinant (His & Trx) Human E. coli
Suppressor of cytokine signaling 3, also known as SOCS-3, Cytokine-inducible SH2 protein 3, CIS-3, STAT-induced STAT inhibitor 3, SOCS3 and CIS3, is a protein which is widely expressed with high expression in heart, plac...
TMPY-01590 GAD65 Protein, Mouse, Recombinant (His & GST) Mouse Baculovirus-Insect Cells
Glutamate decarboxylase 2, also known as glutamate decarboxylase 65 kDa isoform, 65 kDa glutamic acid decarboxylase, GAD2 and GAD65, is a member of thegroup II decarboxylase family. GAD2 is identified as a major autoanti...
TMPY-03515 GAD65 Protein, Mouse, Recombinant Mouse Baculovirus-Insect Cells
Glutamate decarboxylase 2, also known as glutamate decarboxylase 65 kDa isoform, 65 kDa glutamic acid decarboxylase, GAD2 and GAD65, is a member of thegroup II decarboxylase family. GAD2 is identified as a major autoanti...
TMPY-00150 IGF2/IGF-II Protein, Human, Recombinant Human Yeast
Insulin-like growth factor 2 (IGF-2/IGF-II) is a member of the insulin family of polypeptide growth factors, which are involved in development and growth. It is an imprinted gene, expressed only from the paternal allele,...
TMPY-04813 ACAT2 Protein, Rat, Recombinant (His) Rat E. coli
Acyl-coenzyme A: cholesterol acyltransferase (ACAT) is an intracellular enzyme that produces cholesteryl esters in various tissues. In mammals, two ACAT genes (ACAT1 and ACAT2) have been identified. Together, these two e...
TMPY-02878 ANGPTL4 Protein, Human, Recombinant (hFc) Human HEK293
ANGPTL4, also known as ANGPTL2, is a protein with hypoxia-induced expression in endothelial cells. It contains 1 fibrinogen C-terminal domain and is expressed at high levels in the placenta, heart, liver, muscle, pancrea...
TMPY-04030 ANGPTL4 Protein, Mouse, Recombinant (His) Mouse HEK293
ANGPTL4, also known as ANGPTL2, is a protein with hypoxia-induced expression in endothelial cells. It contains 1 fibrinogen C-terminal domain and is expressed at high levels in the placenta, heart, liver, muscle, pancrea...
TMPH-02888 SFRP5 Protein, Mouse, Recombinant (His) Mouse E. coli
Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-sign...
TMPH-03160 Glucomannokinase Protein, Prevotella bryantii, Recombinant Prevotella bryantii E. coli
Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-sign...
TMPH-03500 IL-6 Protein, Sheep, Recombinant (GST) Sheep E. coli
Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-sign...
TMPY-04392 RSK3 Protein, Human, Recombinant (GST) Human Baculovirus-Insect Cells
Ribosomal protein S6 kinase alpha-2, also known as 9 kDa ribosomal protein S6 kinase 2, MAP kinase-activated protein kinase 1c, MAPK-activated protein kinase 1c, Ribosomal S6 kinase 3, RSK-3, RPS6KA2 and MAPKAPK1C, is a ...
TMPY-00950 WISP1/CCN4 Protein, Human, Recombinant (His) Human HEK293
CCN4/Wnt-induced secreted protein 1 (WISP1) is a secreted, cysteine-rich, heparin-binding glycoprotein, belonging to the CCN (CTGF/CYR61/NOV) family of growth factors, and is involved in diverse biological functions such...
TMPY-05126 SIRP alpha Protein, Human, Recombinant (G75A, His), Biotinylated Human HEK293
Tyrosine-protein phosphatase non-receptor type substrate 1, also known as SHP substrate 1, Inhibitory receptor SHPS-1, Brain Ig-like molecule with tyrosine-based activation motifs, Macrophage fusion receptor, CD172 antig...
TMPY-06054 SIRP alpha V8 Protein, Human, Recombinant (His) Human HEK293
Tyrosine-protein phosphatase non-receptor type substrate 1, also known as SHP substrate 1, Inhibitory receptor SHPS-1, Brain Ig-like molecule with tyrosine-based activation motifs, Macrophage fusion receptor, CD172 antig...
TMPY-05745 SIRP alpha Protein, Rat, Recombinant (hFc) Rat HEK293
Tyrosine-protein phosphatase non-receptor type substrate 1, also known as SHP substrate 1, Inhibitory receptor SHPS-1, Brain Ig-like molecule with tyrosine-based activation motifs, Macrophage fusion receptor, CD172 antig...
TMPY-03666 SIRP alpha Protein, Rat, Recombinant (His) Rat HEK293
Tyrosine-protein phosphatase non-receptor type substrate 1, also known as SHP substrate 1, Inhibitory receptor SHPS-1, Brain Ig-like molecule with tyrosine-based activation motifs, Macrophage fusion receptor, CD172 antig...
TMPY-06248 SIRP alpha V2 Protein, Human, Recombinant (His), Biotinylated Human HEK293
Tyrosine-protein phosphatase non-receptor type substrate 1, also known as SHP substrate 1, Inhibitory receptor SHPS-1, Brain Ig-like molecule with tyrosine-based activation motifs, Macrophage fusion receptor, CD172 antig...
TMPY-06055 SIRP alpha V8 Protein, Human, Recombinant (mFc) Human HEK293
Tyrosine-protein phosphatase non-receptor type substrate 1, also known as SHP substrate 1, Inhibitory receptor SHPS-1, Brain Ig-like molecule with tyrosine-based activation motifs, Macrophage fusion receptor, CD172 antig...
TMPY-02636 SIRP alpha Protein, Mouse, Recombinant (hFc) Mouse HEK293
Tyrosine-protein phosphatase non-receptor type substrate 1, also known as SHP substrate 1, Inhibitory receptor SHPS-1, Brain Ig-like molecule with tyrosine-based activation motifs, Macrophage fusion receptor, CD172 antig...
TMPY-05263 SIRP alpha Protein, Human, Recombinant (mFc) Human HEK293
Tyrosine-protein phosphatase non-receptor type substrate 1, also known as SHP substrate 1, Inhibitory receptor SHPS-1, Brain Ig-like molecule with tyrosine-based activation motifs, Macrophage fusion receptor, CD172 antig...
TMPY-06284 SIRP alpha Protein, Human, Recombinant (hFc & Avi), Biotinylated Human HEK293
Tyrosine-protein phosphatase non-receptor type substrate 1, also known as SHP substrate 1, Inhibitory receptor SHPS-1, Brain Ig-like molecule with tyrosine-based activation motifs, Macrophage fusion receptor, CD172 antig...
TMPY-06053 SIRP alpha V2 Protein, Human, Recombinant (mFc) Human HEK293
Tyrosine-protein phosphatase non-receptor type substrate 1, also known as SHP substrate 1, Inhibitory receptor SHPS-1, Brain Ig-like molecule with tyrosine-based activation motifs, Macrophage fusion receptor, CD172 antig...
TMPH-01446 Human herpesvirus 2 (HHV-2) (strain HG52) Envelope glycoprotein B (His & SUMO) HHV-2 E. coli
ATP-independent molecular chaperone preventing the aggregation of misfolded and hydrophobic patches-containing proteins. Functions as part of a cytosolic protein quality control complex, the BAG6/BAT3 complex, which main...
TMPH-01447 Human herpesvirus 2 (HHV-2) (strain HG52) Envelope glycoprotein C (His) HHV-2 in vitro E. coli expression system
ATP-independent molecular chaperone preventing the aggregation of misfolded and hydrophobic patches-containing proteins. Functions as part of a cytosolic protein quality control complex, the BAG6/BAT3 complex, which main...
GAD65 Protein, Human, Recombinant (GST)
TMPY-04699
Species: Human
Expression System: Baculovirus-Insect Cells
ANGPTL4 Protein, Human, Recombinant (His)
TMPY-03523
Species: Human
Expression System: HEK293
SIRP alpha Protein, Mouse, Recombinant (His)
TMPY-02632
Species: Mouse
Expression System: HEK293
SIRP alpha V2 Protein, Human, Recombinant (His)
TMPY-06052
Species: Human
Expression System: HEK293
SIRP alpha Protein, Human, Recombinant (G75A, His)
TMPY-01573
Species: Human
Expression System: HEK293
SIRP alpha Protein, Human, Recombinant (hFc)
TMPY-06051
Species: Human
Expression System: HEK293
SIRP alpha Protein, Cynomolgus, Recombinant (His)
TMPY-05841
Species: Cynomolgus
Expression System: HEK293
Cathepsin H Protein, Human, Recombinant (His)
TMPY-06479
Species: Human
Expression System: HEK293
Cathepsin H Protein, Mouse, Recombinant (His)
TMPY-04081
Species: Mouse
Expression System: HEK293
IGF1/IGF-I Protein, Mouse, Recombinant
TMPY-04878
Species: Mouse
Expression System: Yeast
IGF1 LR3 Protein, Human, Recombinant
TMPY-04942
Species: Human
Expression System: Yeast
IGF1/IGF-I Protein, Human, Recombinant
TMPY-06982
Species: Human
Expression System: E. coli
FGF-19 Protein, Human, Recombinant (His)
TMPJ-00715
Species: Human
Expression System: E. coli
CD38 Protein, Mouse, Recombinant (hFc)
TMPJ-00190
Species: Mouse
Expression System: Human Cells
Glucokinase Protein, Human, Recombinant
TMPY-04394
Species: Human
Expression System: E. coli
SOCS3 Protein, Human, Recombinant (His & Trx)
TMPY-02194
Species: Human
Expression System: E. coli
GAD65 Protein, Mouse, Recombinant (His & GST)
TMPY-01590
Species: Mouse
Expression System: Baculovirus-Insect Cells
GAD65 Protein, Mouse, Recombinant
TMPY-03515
Species: Mouse
Expression System: Baculovirus-Insect Cells
IGF2/IGF-II Protein, Human, Recombinant
TMPY-00150
Species: Human
Expression System: Yeast
ACAT2 Protein, Rat, Recombinant (His)
TMPY-04813
Species: Rat
Expression System: E. coli
ANGPTL4 Protein, Human, Recombinant (hFc)
TMPY-02878
Species: Human
Expression System: HEK293
ANGPTL4 Protein, Mouse, Recombinant (His)
TMPY-04030
Species: Mouse
Expression System: HEK293
SFRP5 Protein, Mouse, Recombinant (His)
TMPH-02888
Species: Mouse
Expression System: E. coli
Glucomannokinase Protein, Prevotella bryantii, Recombinant
TMPH-03160
Species: Prevotella bryantii
Expression System: E. coli
IL-6 Protein, Sheep, Recombinant (GST)
TMPH-03500
Species: Sheep
Expression System: E. coli
RSK3 Protein, Human, Recombinant (GST)
TMPY-04392
Species: Human
Expression System: Baculovirus-Insect Cells
WISP1/CCN4 Protein, Human, Recombinant (His)
TMPY-00950
Species: Human
Expression System: HEK293
SIRP alpha Protein, Human, Recombinant (G75A, His), Biotinylated
TMPY-05126
Species: Human
Expression System: HEK293
SIRP alpha V8 Protein, Human, Recombinant (His)
TMPY-06054
Species: Human
Expression System: HEK293
SIRP alpha Protein, Rat, Recombinant (hFc)
TMPY-05745
Species: Rat
Expression System: HEK293
SIRP alpha Protein, Rat, Recombinant (His)
TMPY-03666
Species: Rat
Expression System: HEK293
SIRP alpha V2 Protein, Human, Recombinant (His), Biotinylated
TMPY-06248
Species: Human
Expression System: HEK293
SIRP alpha V8 Protein, Human, Recombinant (mFc)
TMPY-06055
Species: Human
Expression System: HEK293
SIRP alpha Protein, Mouse, Recombinant (hFc)
TMPY-02636
Species: Mouse
Expression System: HEK293
SIRP alpha Protein, Human, Recombinant (mFc)
TMPY-05263
Species: Human
Expression System: HEK293
SIRP alpha Protein, Human, Recombinant (hFc & Avi), Biotinylated
TMPY-06284
Species: Human
Expression System: HEK293
SIRP alpha V2 Protein, Human, Recombinant (mFc)
TMPY-06053
Species: Human
Expression System: HEK293
Human herpesvirus 2 (HHV-2) (strain HG52) Envelope glycoprotein B (His & SUMO)
TMPH-01446
Species: HHV-2
Expression System: E. coli
Human herpesvirus 2 (HHV-2) (strain HG52) Envelope glycoprotein C (His)
TMPH-01447
Species: HHV-2
Expression System: in vitro E. coli expression system
Cat No. Product Name
L9700 Endoplasmic Reticulum Stress Compound Library

193 compounds
A unique collection of 193 endoplasmic reticulum stress (ER stress) related compounds used for high throughput screening (HTS) and high content screening (HCS);
TargetMol