imr-32

Paeoniflorin (Peoniflorin) is a herbal constituent extracted from the root of Paeonia albiflora Pall.

Ellipticine (Elliptisine) is a potent antineoplastic agent exhibiting multiple mechanisms of action, IC50 of 0.67±0.06, 1.25±0.13, 1.25±0.13, 0.67±0.06, 0.27±0.02, 0.49±0.04, 0.44±0.03, and 1.48±0.62 μM for Leukemia HL-60, Breast adenocarcinoma MCF-7, Breast adenocarcinoma MCF-7, Leukemia HL-60, Neuroblastoma IMR-32, Neuroblastoma UKF-NB-4, Neuroblastoma UKF-NB-3, and Glioblastoma U87 mg cell, respectively.

Antiviralagent 64 (Compound 12) is a diarylheptane compound isolated from *Alpinia officinarum*. In human neuroblastoma IMR-32 cells, it exhibits cytotoxicity with an IC50 of 0.23 μM. Antiviralagent 64 also demonstrates antiviral activity, effectively inhibiting RSV, poliovirus, measles virus, HSV-1, and influenza virus H1N1, with EC50 values of 13.3, 3.7, 6.3, 5.7, and <10 μg mL, respectively.