il9

IL-9 is a pleiotropic cytokine that influences various distinct functions of different target cells such as T cells, B cells, mast cells and airway epithelial cells by activating STAT1, STAT3 and STAT5. Because of its pleiotropic functions, IL-9 has been demonstrated to be involved in several diseases, such as cancer, autoimmunity and other pathogen-mediated immune-regulated diseases. In this review, we focus on the role of Th9 and IL-9-producing cells in allergic asthma. IL-9 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 14.01 kDa and the accession number is A0A7N9IA33.

IL-9 Protein, Human, Recombinant is expressed in CHO Cells. The accession number is P15248.

IL-9 Protein, Mouse, Recombinant is expressed in HEK293 Cells. The accession number is P15247.

Expression system: HEK293 Cells
Length: 19-144, Full Length of Mature Protein
Activity: ELISA

Expression system: HEK293 Cells
Length: 19-144, Full Length of Mature Protein
Activity: Not Tested

Expression system: Baculovirus Insect Cells
Length: 1-144, Full Length
Activity: Cell Activity

Expression system: Baculovirus Insect Cells
Length: 1-144, Full Length
Activity: Cell Activity

IL9R (Interleukin 9 Receptor) is a Protein Coding gene. The protein encoded by this gene is a cytokine receptor that specifically mediates the biological effects of interleukin 9 (IL9). IL9 is involved in mast cell maturation and the enhancement of IgE production by B cells. Furthermore, linkage data in the human and mice have suggested that IL9 may contribute to asthma. The ligand binding of this receptor leads to the activation of various JAK kinases and STAT proteins, which connect to different biologic responses. IL9R is known to be autosomal in mice and is X-linked only in primates. The more recent X linkage and more telomeric position of the IL9R gene may explain its autosomal, 'un-inactivated' transcriptional status.