hypericum

Hypericin (Cyclosan) is a natural anthraquinone compound, an extract of Hypericum perforatum, which inhibits PKC, MAO, dopamine-beta-hydroxylase, reverse transcriptase, telomerase, and CYP, etc. Hypericin exhibits antimicrobial, antiviral, antitumor, and antidepressant activities.

Hyperoside (Hyperin) is a naturally occuring flavonoid compound which shows multiple bioactivities, including myocardial protection, anti-redox, and anti-inflammatory activities.

Stigmastanol is a phytosterol.

2 -O-Galloylhyperin (FT-0689359) found in Pyrola. It increases ruminal fiber fermentability by formed wall-bound lignin in primary maize cell walls.

Vincetoxicoside B, isolated from Polygonum paleaceum Wall. Vincetoxicoside B , quercetin, kaempferol , and (-)-epicatechin show synergistic antifungal activities with the FICI values <0.5.

3,4-O-Isopropylidene-shikimic acid (3,4-O-Isopropylidene shikimic acid) exhibits significant anti-inflammatory, anti-thrombosis, antioxidant, and analgesic effects, and provides protective benefits against trinitrobenzenesulfonic acid-induced experimental colitis in rats, likely because of its antioxidant properties.

3, 8''-Biapigenin can modulate intracellular ROS production.

Hyperforin, a natural product from Hypericum, is commonly used as an antidepressant and also has neurological, inflammatory, antimicrobial, antitumor and antiangiogenic effects. Hyperforin acts as a monoamine reuptake inhibitor (MRI) in vitro, including serotonin, norepinephrine, dopamine, GABA, and glutamate, with an IC 50 of ≈0.1 μg mL. Hyperforin is also capable of inducing the cytochrome P450 enzymes, CYP3A4 and CYP2C9, through binding to and activation of the pregnane X receptor. Hyperforin is capable of activating TRPC6 channels by binding to a specific motif.

Mauritianin, a kaempferol glycoside isolated from the flowers and leaves of Acalypha indica, is a topoisomerase I inhibitor with cytoprotective activity.

Protohypericin, a naphthodianthrone derivative found in the plant Hypericum perforatum, exhibits photocytotoxicity and is utilized in tumor necrosis targeted radiotherapy through its radioiodinated form.

Protopseudohypericin is a natural product

Pseudohypericin has photocytotoxic, and antiretroviral activities, it has potential therapeutic value in diseases such as AIDS.

Quercetin 3-O-(6''-galloyl)-beta-D-galactopyranoside effectively induces apoptosis through the p53, MAPKs, and mitochondrial apoptotic pathways.

Quercetin 3-O-(6''-O-galloyl)-β-D-glucoside (Quercetin 3-O-(6''-galloyl)-beta-D-glucopyranoside) is a natural product with potent inhibitory activity against the growth of Microcystis aeruginosa.

Taxifolin 7-O-rhamnoside (Taxifolin 7-O-α-L-rhamnoside) is a natural product derived from Hypericum japonicum.

BLV is a natural product for research related to life sciences. The catalog number is TN2484 and the CAS number is 146905-24-0.

2,2-Dimethyl-6-phenylpyrano[3,4-b]pyran-8-one is a natural product derived from the metabolites of Hypericum revolutum ssp.

3,6-Dihydroxy-1,7-dimethoxyxanthone is a natural product from Hypericum ascyro.

5-Hydroxy-1-methoxyxanthone, 1,5-dihydroxyxanthone and 6-deoxyjacareubin are all antifungal against Cladosporium cucumerinum, while they show differing degrees of inhibition of monoamine oxidase A and B.

8-Hydroxyhyperforin 8,1-hemiacetal is a natural product for research related to life sciences. The catalog number is TN3282 and the CAS number is 59014-02-7.

Cadensin D is a natural product for research related to life sciences. The catalog number is TN3562 and the CAS number is 102349-35-9.

Saropyrone is a natural product from Hypericum Japonicum.

Vanillic acid glucoside (Vanillic acid 4-β-D-glucoside) is a dimeric oxaloside isolated from Hypericum persica.

1-Eicosanol is a natural product isolated from Hypericum carinatum. 1-Eicosanol has antioxidant activity.