hyodeoxycholic acid

Hyodeoxycholic acid (NSC 60672) has been used in trials studying the treatment of Hypercholesterolemia.

β-Hyodeoxycholic acid-D4 is the deuterium-labeled form of β-Hyodeoxycholic acid (TMSM-3997).

Hyodeoxycholic acid sodium salt, a natural secondary bile acid, enhances high-density lipoprotein function, reduces farnesoid X receptor antagonist bile acids, and induces potent cytotoxicity, apoptosis, and IL-8 synthesis.

Norhyodeoxycholic acid (NHDCA) is a synthetic bile acid and a derivative of hyodeoxycholic acid .1,2 NHDCA is an intermediate in the synthesis of 3β-sulfooxy-7β-hydroxy-24-nor-5-cholen-23-oic acid, which has been used as an internal standard for the quantification of δ5-bile acid conjugates that have been identified in patients with Niemann-Pick disease type C1.3 |1. Schteingart, C.D., and Hofmann, A.F. Synthesis of 24-nor-5β-cholan-23-oic acid derivatives: A convenient and efficient one-carbon degradation of the side chain of natural bile acids. J. Lipid Res. 29(10), 1387-1395 (1988).|2. Une, M., and Hoshita, T. Natural occurrence and chemical synthesis of bile alcohols, higher bile acids, and short side chain bile acids. Hiroshima J. Med. Sci. 43(2), 37-67 (1994).|3. Kakiyama, G., Muto, A., Shimada, M., et al. Chemical synthesis of 3β-sulfooxy-7β-hydroxy-24-nor-5-cholenoic acid: An internal standard for mass spectrometric analysis of the abnormal δ5-bile acids occurring in Niemann-Pick disease. Steroids 74(9), 766-772 (2009).

glycohyodeoxycholic acid is a major metabolite of the secondary bile acid hyodeoxycholic acid in humans.

Hyodeoxycholic acid-D5 is the deuterated form of Hyodeoxycholic acid (TMSM-3213). This compound is a secondary bile acid formed by gut microbiota in the small intestine and acts as an agonist for TGR5 (GPCR19), with an EC50 value of 31.6 µM in CHO cells.

Hyodeoxycholic acid (Standard) is a reference standard for research and analysis in studies involving Hyodeoxycholic acid. Hyodeoxycholic acid (NSC 60672) has been used in trials studying the treatment of Hypercholesterolemia.

glycohyodeoxycholic acid (Standard) is a reference standard for research and analysis in studies involving glycohyodeoxycholic acid. glycohyodeoxycholic acid is a major metabolite of the secondary bile acid hyodeoxycholic acid in humans.

β-Hyodeoxycholic Acid (Standard) is a reference standard of β-Hyodeoxycholic Acid intended for quantitative analysis, quality control, and related biochemical research applications.

Hyodeoxycholic Acid-[D4] (Standard) is a reference standard of Hyodeoxycholic Acid-[D4] intended for quantitative analysis, quality control, and related biochemical research applications.

Taurohyodeoxycholic acid (THDCA) is a bile acid that plays a key role in regulating the hepatic inflammatory microenvironment.THDCA reduces the expression of TNF-α and IL-6 and inhibits the development of hepatocellular carcinoma (HCC). It is able to inhibit non-alcoholic fatty liver disease and regulate bile acid metabolism in combination with astragalus polysaccharides: it reduces CD36 expression in the liver and decreases hepatic lipid accumulation by up-regulating CYP7B1 and down-regulating CYP7A1.

Taurohyodeoxycholic acid sodium salt (Sodium taurohyodeoxycholate hydrate) prevents apoptosis by blocking a calcium-mediated apoptotic pathway as well as caspase-12 activation.

Taurohyodeoxycholic acid sodium salt (Standard) is a reference standard for research and analysis in studies involving Taurohyodeoxycholic acid sodium salt. Taurohyodeoxycholic acid sodium salt (Sodium taurohyodeoxycholate hydrate) prevents apoptosis by blocking a calcium-mediated apoptotic pathway as well as caspase-12 activation.

Taurohyodeoxycholic acid (Standard) is a reference standard of Taurohyodeoxycholic acid intended for quantitative analysis, quality control, and related biochemical research applications.

Taurohyodeoxycholic Acid-[D4] Sodium Salt (Standard) is a reference standard of Taurohyodeoxycholic Acid-[D4] Sodium Salt intended for quantitative analysis, quality control, and related biochemical research applications.

Glycohyodeoxycholic Acid-[D4] (Standard) is a reference standard of Glycohyodeoxycholic Acid-[D4] intended for quantitative analysis, quality control, and related biochemical research applications.

Taurodeoxycholic acid sodium hydrate (Sodium taurodeoxycholate monohydrate), a hydrophilic bile salt, influences bile salt and biliary lipid secretion in rats.