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Search Result
Results for "
human gpr40
" in TargetMol Product Catalog- Inhibitors & Agonists5
- Antibody Products1
AM-4668
AM4668
T142021011531-27-3
AM-4668, a GPR40 (FFA1) agonist with oral availability, was optimized to reduce central nervous system (CNS) permeability, with a mouse brain plasma ratio of only 0.02, and significantly reduced blood glucose levels in human GPR40 knock-in mice.
- Inquiry Price
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GPR40 agonist 1
T114591853982-41-8
GPR40 agonist 1 is an effective new GPR40 agonist (EC50s: 17 nM and 2 nM for rGPR40 and hGPR40).
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LY2922470
T158101423018-12-5
LY2922470 reduces glucose levels along with significant enhancements in insulin and GLP-1, which is the potential for the treatment of type 2 diabetes mellitus (T2DM). LY2922470 is an effective, selective, and orally available agonist of the G protein-cou
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AMG 837 hemicalcium
T628481291087-14-3
AMG 837 hemicalcium is a potent, orally active GPR40 FFA1 partial agonist that inhibits the specific binding of [3H]AMG 837 to the human FFA1 receptor (pIC50: 8.13). It promotes insulin secretion and reduces glucose levels in rodents.
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TUG-770
TUG770, TUG 770
TQ02411402601-82-4
TUG-770 is a GPR40 FFA1 agonist with potential anti-inflammatory activity.TUG-770 can be used to study type 2 diabetes, dementia, and Alzheimer's disease.
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