hepatotoxin

Phenylbutazone (Butazolidine) is a butyl-diphenyl-pyrazolidinedione that has anti-inflammatory, antipyretic, and analgesic activities. It has been used in ankylosing spondylitis, rheumatoid arthritis, and reactive arthritis.

Thioacetamide (TAA) is an indirect hepatotoxin commonly used to induce experimental liver injury. It is metabolized by CYP2E1 into reactive metabolites that covalently bind to proteins and lipids, leading to oxidative stress and centrilobular necrosis, hepatocyte death, and M1 M2 macrophage-dominated inflammation. TAA is widely used to establish models of chronic liver fibrosis, hepatic encephalopathy, and liver cancer.

Dimethylnitrosamine (NDMA) is a potent hepatotoxin, carcinogen, and mutagen, and is commonly used to establish liver tumor models.

Dimethylnitrosamine (Standard) is the standard substance of Dimethylnitrosamine, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Dimethylnitrosamine (NDMA) is a potent hepatotoxin, carcinogen, and mutagen, and is commonly used to establish liver tumor models.

Lophyrotomin is a hepatotoxin isolated from the European Birch sawfly Arge pullata.