galanin (human) (acetate)

Galanin (Human) (Acetate) is a 30-amino acid neuropeptide and galanin (GAL) receptor agonist.It inhibits forskolin-induced cAMP production in HEK293E cells expressing recombinant human GAL1 receptors (EC50= 0.031 nM) and stimulates inositol phosphate accumulation in CHO cells expressing recombinant human GAL2receptors (EC50= 12.3 nM).Human galanin induces contractions in isolated rat longitudinal fundus strips with an EC50value of 13.8 nM.Intrathecal administration of human galanin (3, 10, and 30 nmol/animal) reduces paw licking and flinching in the second, but not first, phase of the formalin test in rats.

Galanin (1-30), human acetate (Galanin ) is a 30-amino acid neuropeptide. Galanin (1-30), human acetate acts as an agonist of GalR1 and GalR2 receptors, with Kis of both 1 nM.

Alarin (human) acetate is a neuropeptide belonging to the hypothalamic galanin family, widely expressed in the central nervous system and peripheral tissues of humans and rodents. It possesses the signal sequence of the GALP precursor peptide and the first five amino acids of mature GALP lacking exon 3 .Alarin exhibits vasoactive, anti-inflammatory, anti-oedematous, and antibacterial properties, alongside central regulatory functions in energy homeostasis, glucose homeostasis, body temperature, and reproductive hormone secretion.