fipronil

Fipronil (Fluocyanobenpyrazole) is a broad-use insecticide that belongs to the phenylpyrazole chemical family. Fipronil is a broad-spectrum insecticide that disrupts the insect central nervous system by blocking GABA-gated chloride channels and glutamate-gated chloride (GluCl) channels, resulting in central nervous system toxicity. This causes hyperexcitation of contaminated insects' nerves and muscles. Specificity of fipronil on insects may come from a better efficacy on GABA receptor, but also because GluCl channels do not exist in mammals.

Fipronil desulfinyl, a photodegradation product of the insecticide Fipronil, exhibits similar in vivo toxicity to Fipronil and possesses higher environmental toxicity.

Fipronil sulfone is an insecticide fipronil. Its metabolite fipronil sulphone is an inhibitor of rat ɑ1β2γ2L GABA(A) receptor.

Fipronil desulfinyl (Standard) is the standard substance of Fipronil desulfinyl, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Fipronil desulfinyl, a photodegradation product of the insecticide Fipronil, exhibits similar in vivo toxicity to Fipronil and possesses higher environmental toxicity.

Fipronil sulfone (Standard) is the standard substance of Fipronil sulfone, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Fipronil sulfone is an insecticide fipronil. Its metabolite fipronil sulphone is an inhibitor of rat ɑ1β2γ2L GABA(A) receptor.

Flufiprole is used as a phenylpyrazole pesticide. It has enantioselective metabolism in human and rat liver microsomes.