fao

Etomoxir sodium salt ((R)-Etomoxir sodium salt) is a carnitine palmitoyltransferase 1a (CPT-1a) inhibitor that inhibits fatty acid oxidation (FAO). Etomoxir sodium salt has antitumor activity.

Ranolazine (RS 43285-003) is a calcium uptake inhibitor via the sodium/calcium channel, used to treat chronic angina. It affects the sodium-dependent calcium channels during myocardial ischemia in rabbits by altering the intracellular sodium level.

DHP-B exhibits anticancer properties and can induce apoptosis. It forms a covalent bond with the Cys96 of CPT1A, obstructing FAO and disrupting the interaction between mitochondrial CPT1A and vdac1. This results in increased mitochondrial permeability in CRC cells, along with reduced oxygen consumption and energy metabolism. DHP-B can be isolated from the plant Peperomia dindygulensis.

Ciprofibrate impurity A is an impurity of Ciprofibrate, a PPARα agonist[1].