endocrine disorders

RPR107393 free base is a selective and potent inhibitor of squalene synthase (SQS) for the study of neurological disorders and endocrine and metabolic disorders.

SPD-473 citrate (BTS 74398 citrate) is a dopamine reuptake inhibitor, a norepinephrine transporter protein (NET) inhibitor, and a 5-hydroxytryptamine reuptake inhibitor, and is used in the study of neurological disorders and endocrine and metabolic diseases.

PS423 (PS210AM) is a substrate-selective inhibitor of PDK1 and a selective PDK1 activator that inhibits the phosphorylation and activation of S6K, and is used in the study of endocrine and metabolic disorders.

Eflucimibe (L0081) is an acyl coenzyme A: cholesterol acyltransferase inhibitor for the treatment of cardiovascular disease and endocrine and metabolic disorders, and can be used to study atherosclerosis and hyperlipidemia.

Eldacimibe (WAY-ACA-147) is an ACAT2 inhibitor for the treatment of cardiovascular disease and endocrine and metabolic disorders, study of atherosclerosis and hypercholesterolemia.

Ronacaleret HCl (SB-751689) is a small molecule CaSR antagonist for the treatment of endocrine and metabolic diseases, skin and musculoskeletal disorders.

Bisphenol A is an endogenous metabolic compound of phenols and is widely used in the production of epoxy resins and polycarbonate plastics. It is reproductive, developmental and systemic toxicant and is often classified as an endocrine disruptor. It has been linked to many diseases, including respiratory disease, cardiovascular disease, diabetes, kidney disease, obesity and reproductive disorders.

L-Thyroxine sodium salt pentahydrate (Sodium levothyroxine pentahydrate) is a thyroid hormone with anticholesterol activity that inhibits the release of thyroid hormones from thyroid cancer nodules and is used in immune and endocrine disorders such as hypothyroidism, myxedema, cretinism and obesity. diseases, such as hypothyroidism, myxedema, cretinism and obesity.

PF-3882845 is an orally available and selective salicorticoid receptor (MR) antagonist that binds to the progesterone receptor (PR) and can be used to study endocrine diseases and urogenital disorders.

Buntanetap ((+)-Phenserine) is an orally active inhibitor of polyneurotoxic proteins (TINAPs) for the study of neurological disorders, endocrine and metabolic disorders, and cardiovascular diseases.

Nesuparib (JPI-547 OCN-201) is a potent PARP inhibitor with inhibitory effects on PARP and TNKS1.Nesuparib has antitumor activity and can be used in the treatment of tumors, endocrine and metabolic disorders, genitourinary disorders, and can be used in the study of neuropathic pain, neurodegenerative disorders, and cardiovascular diseases.

BTK-IN-6 is a potent inhibitor of Bruton's tyrosine kinase (BTK) with research potential in immune diseases, cardiovascular diseases, cancer, viral infections, inflammation, metabolic endocrine dysfunction, and neurological disorders (for more information).

D-Ribose 5-phosphate disodium dihydrate is a key intermediate in the oxidative branch and an end product in the nonoxidative branch of the pentose phosphate pathway (PPP), playing a crucial role in the synthesis of nucleotides and nucleic acids [1].

K1-70 is a humanized antibody targeting TSHR, used in the study of autoimmune diseases and endocrine disorders.

Tschimganidin is an ERα agonist with an IC50 of 1.4 μM, found in Apiaceae plants. It is a terpenoid compound with anti-obesity activity and is applicable in research related to endocrine and metabolic disorders.