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(3)
By Target- EBI2/GPR183
- Endogenous Metabolite(1)
- Others(2)
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Results for "
ebi2
" in TargetMol Product Catalog- Inhibitors & Agonists5
- Natural Products1
SAE-14
3-(3,4-difluorophenyl)-N-[3-fluoro-5-(morpholin-4-yl)phenyl]propanamide
T99751241280-25-0
SAE-14 is a specific GPR183 antagonist. SAE-14 inhibits GPR183 with an IC50 of 28.5 nM in a calcium mobilization assay[1].
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7α,25-Dihydroxycholesterol
7α,25-OHC
T1406364907-22-8
7α,25-dihydroxycholesterol (7α,25-OHC) is a potent and selective agonist, as well as an endogenous ligand, of the orphan GPCR receptor EBI2 (GPR183). It serves as a chemokine directing the migration of B cells, T cells, and dendritic cells and exhibits high potency in activating EBI2 (EC50=140 pM; Kd=450 pM) [1][2].
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GSK682753A
T114981334294-76-6
GSK682753A is a selective and highly potent inverse agonist of the Epstein-Barr virus-induced receptor 2 (EBI2) with an IC50 of 53.6 nM.
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