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By Target- TRP/TRPV Channel
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Results for "
dr-6
" in TargetMol Product Catalog- Inhibitors & Agonists2
- Recombinant Protein6
MDR-652
T223601933528-96-1
MDR-652 is a highly specific and efficacious agonist of nonpungent transient receptor potential vanilloid 1 (TRPV1), with Ki values of 11.4 nM and 23.8 nM for hTRPV1 and rTRPV1, respectively, and EC50s of 5.05 nM and 93 nM for hTRPV1 and rTRPV1, respectively. MDR-652 is a potent topical analgesic.
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KHK-6
T89399
KHK-6 is an inhibitor of serine threonine kinase hematopoietic progenitor kinase 1 (HPK 1), with an IC50 of 20 nM. This compound enhances cytokine production induced by CD3 CD28 and upregulates the expression of CD69, CD25, and HLA-DR markers on CD4+ and CD8+ T cells. Additionally, KHK-6 augments the T cell-mediated cytotoxicity against SKOV3 and A549 cells.
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